Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review
Multiple organ dysfunction syndrome (MODS) is a continuous process with incremental degrees of physiologic derangements in individual organs. The alteration in organ function can vary widely from a mild degree of organ dysfunction to completely irreversible organ failure. MODS, as defined, is a clin...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Sahel Medical Journal |
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| Online Access: | http://www.smjonline.org/article.asp?issn=1118-8561;year=2018;volume=21;issue=4;spage=222;epage=226;aulast=Masoodi |
| _version_ | 1818651606035464192 |
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| author | Ibrahim Masoodi |
| author_facet | Ibrahim Masoodi |
| author_sort | Ibrahim Masoodi |
| collection | DOAJ |
| description | Multiple organ dysfunction syndrome (MODS) is a continuous process with incremental degrees of physiologic derangements in individual organs. The alteration in organ function can vary widely from a mild degree of organ dysfunction to completely irreversible organ failure. MODS, as defined, is a clinical syndrome characterized by the development of progressive and potentially reversible physiologic dysfunction in two or more organs or organ systems that are induced by a variety of acute insults, including sepsis. The cornerstone in the management remains correction of the triggering agent. The clinical scenario of a young male who presented with progressive shortness of breath, renal failure, and epistaxis (MODS) at presentation is discussed in this report. The diagnosis of this patient was clinically quite challenging. On evaluation, he proved to have multi-organ failure due to Brucella melitensis. The patient improved with conventional B. melitensis treatment. The Brucella infection is a male predominant disease and frequently presents with typical symptoms of fever, fatigue, etc., and the diagnosis often is straightforward, but the reports of atypical presentation have been described in the literature. The heaviest disease burden of B. melitensis lies in countries of the Mediterranean basin and Arabian Peninsula. However, the disease is not uncommon in India, Mexico, and Central America. Hence, clinicians need to be aware of this clinical entity all over the globe. The report of the case and brief review of literature are presented in this report. |
| first_indexed | 2024-12-17T02:08:47Z |
| format | Article |
| id | doaj.art-790c280d995e4842a0d5ca1c43de8cf2 |
| institution | Directory Open Access Journal |
| issn | 2321-6689 |
| language | English |
| last_indexed | 2024-12-17T02:08:47Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Sahel Medical Journal |
| spelling | doaj.art-790c280d995e4842a0d5ca1c43de8cf22022-12-21T22:07:37ZengWolters Kluwer Medknow PublicationsSahel Medical Journal2321-66892018-01-0121422222610.4103/smj.smj_11_18Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature reviewIbrahim MasoodiMultiple organ dysfunction syndrome (MODS) is a continuous process with incremental degrees of physiologic derangements in individual organs. The alteration in organ function can vary widely from a mild degree of organ dysfunction to completely irreversible organ failure. MODS, as defined, is a clinical syndrome characterized by the development of progressive and potentially reversible physiologic dysfunction in two or more organs or organ systems that are induced by a variety of acute insults, including sepsis. The cornerstone in the management remains correction of the triggering agent. The clinical scenario of a young male who presented with progressive shortness of breath, renal failure, and epistaxis (MODS) at presentation is discussed in this report. The diagnosis of this patient was clinically quite challenging. On evaluation, he proved to have multi-organ failure due to Brucella melitensis. The patient improved with conventional B. melitensis treatment. The Brucella infection is a male predominant disease and frequently presents with typical symptoms of fever, fatigue, etc., and the diagnosis often is straightforward, but the reports of atypical presentation have been described in the literature. The heaviest disease burden of B. melitensis lies in countries of the Mediterranean basin and Arabian Peninsula. However, the disease is not uncommon in India, Mexico, and Central America. Hence, clinicians need to be aware of this clinical entity all over the globe. The report of the case and brief review of literature are presented in this report.http://www.smjonline.org/article.asp?issn=1118-8561;year=2018;volume=21;issue=4;spage=222;epage=226;aulast=MasoodiAcute brucellosishepatitismulti-organ dysfunction syndromerenal failurethrombocytopenia |
| spellingShingle | Ibrahim Masoodi Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review Sahel Medical Journal Acute brucellosis hepatitis multi-organ dysfunction syndrome renal failure thrombocytopenia |
| title | Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review |
| title_full | Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review |
| title_fullStr | Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review |
| title_full_unstemmed | Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review |
| title_short | Multi-organ dysfunction syndrome as the first presentation of acute brucellosis, a case report and literature review |
| title_sort | multi organ dysfunction syndrome as the first presentation of acute brucellosis a case report and literature review |
| topic | Acute brucellosis hepatitis multi-organ dysfunction syndrome renal failure thrombocytopenia |
| url | http://www.smjonline.org/article.asp?issn=1118-8561;year=2018;volume=21;issue=4;spage=222;epage=226;aulast=Masoodi |
| work_keys_str_mv | AT ibrahimmasoodi multiorgandysfunctionsyndromeasthefirstpresentationofacutebrucellosisacasereportandliteraturereview |