The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus

Diabetes mellitus is a metabolic disease that can lead to high morbidity, mortality and long-term complications. Available treatment strategies, which are mainly based on treating hyperglycemia, with insulin and other pharmacological agents are not completely efficient and can even lead to developme...

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Main Authors: Olawale R. Ajuwon, Ademola O. Ayeleso, Gbenga A. Adefolaju
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/12/3207
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author Olawale R. Ajuwon
Ademola O. Ayeleso
Gbenga A. Adefolaju
author_facet Olawale R. Ajuwon
Ademola O. Ayeleso
Gbenga A. Adefolaju
author_sort Olawale R. Ajuwon
collection DOAJ
description Diabetes mellitus is a metabolic disease that can lead to high morbidity, mortality and long-term complications. Available treatment strategies, which are mainly based on treating hyperglycemia, with insulin and other pharmacological agents are not completely efficient and can even lead to development of unwanted side effects. Scientific evidence suggests that bioactive compounds from teas and other plant-based foods, which are known source of natural antioxidants, could be an attractive strategy to preferentially treat and manage type 2 diabetes mellitus (T2DM) and thus, have significant therapeutic implications. In this review, we attempt an in-depth analysis and discussion of the current progress in our understanding of the antidiabetic potential of two commercialized South Africa herbal tisanes—Rooibos and Honeybush and their polyphenols.
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spelling doaj.art-7913888d0cf24b26a6a8dc370e3356212022-12-21T17:13:39ZengMDPI AGMolecules1420-30492018-12-012312320710.3390/molecules23123207molecules23123207The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes MellitusOlawale R. Ajuwon0Ademola O. Ayeleso1Gbenga A. Adefolaju2Redox Biology Research Unit, Department of Biochemistry, Federal University, Oye-Ekiti 371010, NigeriaDepartment of Biochemistry, Adeleke University, Ede, Osun State 232101, NigeriaDepartment of Pre-Clinical Sciences, University of Limpopo, Sovenga 0727, South AfricaDiabetes mellitus is a metabolic disease that can lead to high morbidity, mortality and long-term complications. Available treatment strategies, which are mainly based on treating hyperglycemia, with insulin and other pharmacological agents are not completely efficient and can even lead to development of unwanted side effects. Scientific evidence suggests that bioactive compounds from teas and other plant-based foods, which are known source of natural antioxidants, could be an attractive strategy to preferentially treat and manage type 2 diabetes mellitus (T2DM) and thus, have significant therapeutic implications. In this review, we attempt an in-depth analysis and discussion of the current progress in our understanding of the antidiabetic potential of two commercialized South Africa herbal tisanes—Rooibos and Honeybush and their polyphenols.https://www.mdpi.com/1420-3049/23/12/3207tearooiboshoneybushpolyphenoltype 2 diabetes
spellingShingle Olawale R. Ajuwon
Ademola O. Ayeleso
Gbenga A. Adefolaju
The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus
Molecules
tea
rooibos
honeybush
polyphenol
type 2 diabetes
title The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus
title_full The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus
title_fullStr The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus
title_full_unstemmed The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus
title_short The Potential of South African Herbal Tisanes, Rooibos and Honeybush in the Management of Type 2 Diabetes Mellitus
title_sort potential of south african herbal tisanes rooibos and honeybush in the management of type 2 diabetes mellitus
topic tea
rooibos
honeybush
polyphenol
type 2 diabetes
url https://www.mdpi.com/1420-3049/23/12/3207
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