A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl

Neonatal lupus (NL) is a passively acquired autoimmune disease that occurs in infants born from asymptomatic mothers having anti-SSA or anti-SSB antibody. Infants with NL may show symptoms of systemic lupus erythematosus, including skin rash, congenital heart block, hepatic dysfunction, and hematolo...

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Main Authors: Yoonkyeom Shin, Ji-Man Kang, Jong Gyun Ahn
Format: Article
Language:English
Published: Korean Society of Pediatric Emergency Medicine 2021-06-01
Series:Pediatric Emergency Medicine Journal
Subjects:
Online Access:http://pemj.org/upload/pdf/pemj-2020-00171.pdf
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author Yoonkyeom Shin
Ji-Man Kang
Jong Gyun Ahn
author_facet Yoonkyeom Shin
Ji-Man Kang
Jong Gyun Ahn
author_sort Yoonkyeom Shin
collection DOAJ
description Neonatal lupus (NL) is a passively acquired autoimmune disease that occurs in infants born from asymptomatic mothers having anti-SSA or anti-SSB antibody. Infants with NL may show symptoms of systemic lupus erythematosus, including skin rash, congenital heart block, hepatic dysfunction, and hematological abnormalities. Mothers of the infants are asymptomatic or diagnosed with autoimmune diseases. When infants born to asymptomatic mothers who have never been diagnosed with the diseases show symptoms of NL, they may be mistaken for having infections. We report an NL case of a 47-day-old girl who presented to the emergency department with fever and skin rash.
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spelling doaj.art-7917b85157634b7d828f613c2f42522c2023-04-04T23:59:10ZengKorean Society of Pediatric Emergency MedicinePediatric Emergency Medicine Journal2383-48972508-55062021-06-0181384110.22470/pemj.2020.00171114A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girlYoonkyeom Shin0Ji-Man Kang1Jong Gyun Ahn2Department of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, Seoul, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, Seoul, KoreaDepartment of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, Seoul, KoreaNeonatal lupus (NL) is a passively acquired autoimmune disease that occurs in infants born from asymptomatic mothers having anti-SSA or anti-SSB antibody. Infants with NL may show symptoms of systemic lupus erythematosus, including skin rash, congenital heart block, hepatic dysfunction, and hematological abnormalities. Mothers of the infants are asymptomatic or diagnosed with autoimmune diseases. When infants born to asymptomatic mothers who have never been diagnosed with the diseases show symptoms of NL, they may be mistaken for having infections. We report an NL case of a 47-day-old girl who presented to the emergency department with fever and skin rash.http://pemj.org/upload/pdf/pemj-2020-00171.pdfautoantibodieserythemafeverinfant, newbornlupus erythematosus, cutaneous
spellingShingle Yoonkyeom Shin
Ji-Man Kang
Jong Gyun Ahn
A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
Pediatric Emergency Medicine Journal
autoantibodies
erythema
fever
infant, newborn
lupus erythematosus, cutaneous
title A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
title_full A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
title_fullStr A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
title_full_unstemmed A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
title_short A case of neonatal lupus presenting with fever and skin rash in a 47-day-old girl
title_sort case of neonatal lupus presenting with fever and skin rash in a 47 day old girl
topic autoantibodies
erythema
fever
infant, newborn
lupus erythematosus, cutaneous
url http://pemj.org/upload/pdf/pemj-2020-00171.pdf
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