Anandamide capacitates bull spermatozoa through CB1 and TRPV1 activation.

Anandamide (AEA), a major endocannabinoid, binds to cannabinoid and vanilloid receptors (CB1, CB2 and TRPV1) and affects many reproductive functions. Nanomolar levels of anandamide are found in reproductive fluids including mid-cycle oviductal fluid. Previously, we found that R(+)-methanandamide, an...

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Bibliographic Details
Main Authors: María Gracia Gervasi, Claudia Osycka-Salut, Julieta Caballero, Mónica Vazquez-Levin, Elba Pereyra, Silvia Billi, Ana Franchi, Silvina Perez-Martinez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3037938?pdf=render