Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study
Abstract Background Information on incidence of gastrointestinal stromal tumor (GIST), the most common type of mesenchymal tumor in gastrointestinal tract, was limited in China. This study aimed to estimate the incidence of GIST in urban population from mainland China in 2016. Methods Urban Employee...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Cancer Medicine |
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| Online Access: | https://doi.org/10.1002/cam4.3644 |
| _version_ | 1819177547567464448 |
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| author | Lu Xu Yanpeng Ma Shengfeng Wang Jingnan Feng Lili Liu Jinxi Wang Guozhen Liu Dianrong Xiu Wei Fu Siyan Zhan Tao Sun Pei Gao |
| author_facet | Lu Xu Yanpeng Ma Shengfeng Wang Jingnan Feng Lili Liu Jinxi Wang Guozhen Liu Dianrong Xiu Wei Fu Siyan Zhan Tao Sun Pei Gao |
| author_sort | Lu Xu |
| collection | DOAJ |
| description | Abstract Background Information on incidence of gastrointestinal stromal tumor (GIST), the most common type of mesenchymal tumor in gastrointestinal tract, was limited in China. This study aimed to estimate the incidence of GIST in urban population from mainland China in 2016. Methods Urban Employee Basic Medical Insurance (UEBMI) and Urban Residence Basic Medical Insurance (URBMI) in China were used. The denominator of incidence was the total person‐years of insured individuals in 2016 in the database, covering approximately 0.43 billion individuals. The numerator was the number of incident GIST cases in 2016. Results The crude incidence in 2016 was 0.40 per 100,000 person‐years (95% CI, 0.06–1.03). Male incidence was higher than female incidence (0.44 vs. 0.36, rate ratio: 1.22, p < 0.001). The mean age at diagnosis was 55.20 years (SD = 14.26) and the incidence among those aged 50 years or older was 2.63 times (0.84 vs. 0.32, p < 0.001) higher than those aged under 50. The highest incidence was observed in East China (2.29, 95% CI: 0.46–5.54). Conclusions The incidence of GIST in mainland China was lower than Europe, North America and Korea. The mean age at diagnosis of GIST in China was younger than that of Europe and Canada. This study provides useful information to further research, policy formulating and management of GIST. |
| first_indexed | 2024-12-22T21:28:24Z |
| format | Article |
| id | doaj.art-791e4e95760342bf8c3459dca230de75 |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-12-22T21:28:24Z |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-791e4e95760342bf8c3459dca230de752022-12-21T18:11:58ZengWileyCancer Medicine2045-76342021-01-0110273774410.1002/cam4.3644Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based studyLu Xu0Yanpeng Ma1Shengfeng Wang2Jingnan Feng3Lili Liu4Jinxi Wang5Guozhen Liu6Dianrong Xiu7Wei Fu8Siyan Zhan9Tao Sun10Pei Gao11Department of Epidemiology and Biostatistics School of Public Health Peking University Beijing ChinaDepartment of General Surgery Peking University Third Hospital Beijing ChinaDepartment of Epidemiology and Biostatistics School of Public Health Peking University Beijing ChinaDepartment of Epidemiology and Biostatistics School of Public Health Peking University Beijing ChinaDepartment of Epidemiology and Biostatistics School of Public Health Peking University Beijing ChinaShanghai Songsheng Business Consulting Co. Ltd Beijing ChinaPeking University Health Information Technology Co. Ltd Beijing ChinaDepartment of General Surgery Peking University Third Hospital Beijing ChinaDepartment of General Surgery Peking University Third Hospital Beijing ChinaDepartment of Epidemiology and Biostatistics School of Public Health Peking University Beijing ChinaDepartment of General Surgery Peking University Third Hospital Beijing ChinaDepartment of Epidemiology and Biostatistics School of Public Health Peking University Beijing ChinaAbstract Background Information on incidence of gastrointestinal stromal tumor (GIST), the most common type of mesenchymal tumor in gastrointestinal tract, was limited in China. This study aimed to estimate the incidence of GIST in urban population from mainland China in 2016. Methods Urban Employee Basic Medical Insurance (UEBMI) and Urban Residence Basic Medical Insurance (URBMI) in China were used. The denominator of incidence was the total person‐years of insured individuals in 2016 in the database, covering approximately 0.43 billion individuals. The numerator was the number of incident GIST cases in 2016. Results The crude incidence in 2016 was 0.40 per 100,000 person‐years (95% CI, 0.06–1.03). Male incidence was higher than female incidence (0.44 vs. 0.36, rate ratio: 1.22, p < 0.001). The mean age at diagnosis was 55.20 years (SD = 14.26) and the incidence among those aged 50 years or older was 2.63 times (0.84 vs. 0.32, p < 0.001) higher than those aged under 50. The highest incidence was observed in East China (2.29, 95% CI: 0.46–5.54). Conclusions The incidence of GIST in mainland China was lower than Europe, North America and Korea. The mean age at diagnosis of GIST in China was younger than that of Europe and Canada. This study provides useful information to further research, policy formulating and management of GIST.https://doi.org/10.1002/cam4.3644Chinaepidemiologygastrointestinal stromal tumorincidence |
| spellingShingle | Lu Xu Yanpeng Ma Shengfeng Wang Jingnan Feng Lili Liu Jinxi Wang Guozhen Liu Dianrong Xiu Wei Fu Siyan Zhan Tao Sun Pei Gao Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study Cancer Medicine China epidemiology gastrointestinal stromal tumor incidence |
| title | Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study |
| title_full | Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study |
| title_fullStr | Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study |
| title_full_unstemmed | Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study |
| title_short | Incidence of gastrointestinal stromal tumor in Chinese urban population: A national population‐based study |
| title_sort | incidence of gastrointestinal stromal tumor in chinese urban population a national population based study |
| topic | China epidemiology gastrointestinal stromal tumor incidence |
| url | https://doi.org/10.1002/cam4.3644 |
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