Michael Addition of 3-Oxo-3-phenylpropanenitrile to Linear Conjugated Enynones: Approach to Polyfunctional δ-Diketones as Precursors for Heterocycle Synthesis
Reaction of linear conjugated enynones, 1,5-diarylpent-2-en-4-yn-1-ones [Ar<sup>1</sup>C≡CCH=CHC(=O)Ar<sup>2</sup>], with 3-oxo-3-phenylpropanenitrile (NCCH<sub>2</sub>COPh) in the presence of sodium methoxide MeONa as a base in MeOH at room temperature for 4–26 h...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-02-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/27/4/1256 |