Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study

Abstract Background Isolated systolic hypertension (ISH), is the most common form of hypertension in older adults. However, the ISH prevalence is not well known in many developing countries such as Iran. This study was conducted to determine the ISH prevalence and its related risk factors in an Iran...

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Main Authors: Ali Hosseinzadeh, Hossein Ebrahimi, Ahmad Khosravi, Mohammad Hassan Emamian, Hassan Hashemi, Akbar Fotouhi
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Cardiovascular Disorders
Subjects:
Online Access:https://doi.org/10.1186/s12872-022-02856-7
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author Ali Hosseinzadeh
Hossein Ebrahimi
Ahmad Khosravi
Mohammad Hassan Emamian
Hassan Hashemi
Akbar Fotouhi
author_facet Ali Hosseinzadeh
Hossein Ebrahimi
Ahmad Khosravi
Mohammad Hassan Emamian
Hassan Hashemi
Akbar Fotouhi
author_sort Ali Hosseinzadeh
collection DOAJ
description Abstract Background Isolated systolic hypertension (ISH), is the most common form of hypertension in older adults. However, the ISH prevalence is not well known in many developing countries such as Iran. This study was conducted to determine the ISH prevalence and its related risk factors in an Iranian population. Methods Data were obtained from the second phase of the Shahroud eye cohort study (ShECS) in 2014. ShECS is a longitudinal population-based study which the first phase had been conducted in 2009 using the stratified multistage cluster sampling design on 5190 people aged 40 to 70 years. The ISH prevalence was determined based on the eighth Joint National Commission guidelines for different demographic variables. The associated risk factors were estimated by multiple logistic regression and a two-tailed p-value less than 0.05 was considered significant. Results The ISH prevalence was 15.89% (95% CI: 14.88–16.96). It was 15.68% (14.12–17.39) and 15.87% (14.54–17.29) for men and women, respectively. The prevalence of ISH increased significantly with increasing age. The 65–70 compared to 45–69 year age group (OR = 4.21), body mass index (OR = 1.03), diabetes (OR = 1.64), retirement, compared to practitioner job (OR = 1.53), and waist to hip ratio (WHR) (OR = 9.81) were significantly associated with ISH prevalence. Conclusions ISH is highly prevalent among the older adult population in Iran. Given the risk of cardiovascular disease associated with ISH, it is recommended to conduct education and public health interventions to improve the detection, prevention, and treatment of ISH.
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spelling doaj.art-79217fa0ea6e434883fab1c72863bf792022-12-22T03:52:15ZengBMCBMC Cardiovascular Disorders1471-22612022-09-012211810.1186/s12872-022-02856-7Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based studyAli Hosseinzadeh0Hossein Ebrahimi1Ahmad Khosravi2Mohammad Hassan Emamian3Hassan Hashemi4Akbar Fotouhi5Department of Epidemiology, School of Public Health, Shahroud University of Medical SciencesRandomized Controlled Trial Research Center, Shahroud University of Medical SciencesDepartment of Epidemiology, School of Public Health, Shahroud University of Medical SciencesOphthalmic Epidemiology Research Center, Shahroud University of Medical SciencesNoor Ophthalmology Research Center, Noor Eye HospitalDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical SciencesAbstract Background Isolated systolic hypertension (ISH), is the most common form of hypertension in older adults. However, the ISH prevalence is not well known in many developing countries such as Iran. This study was conducted to determine the ISH prevalence and its related risk factors in an Iranian population. Methods Data were obtained from the second phase of the Shahroud eye cohort study (ShECS) in 2014. ShECS is a longitudinal population-based study which the first phase had been conducted in 2009 using the stratified multistage cluster sampling design on 5190 people aged 40 to 70 years. The ISH prevalence was determined based on the eighth Joint National Commission guidelines for different demographic variables. The associated risk factors were estimated by multiple logistic regression and a two-tailed p-value less than 0.05 was considered significant. Results The ISH prevalence was 15.89% (95% CI: 14.88–16.96). It was 15.68% (14.12–17.39) and 15.87% (14.54–17.29) for men and women, respectively. The prevalence of ISH increased significantly with increasing age. The 65–70 compared to 45–69 year age group (OR = 4.21), body mass index (OR = 1.03), diabetes (OR = 1.64), retirement, compared to practitioner job (OR = 1.53), and waist to hip ratio (WHR) (OR = 9.81) were significantly associated with ISH prevalence. Conclusions ISH is highly prevalent among the older adult population in Iran. Given the risk of cardiovascular disease associated with ISH, it is recommended to conduct education and public health interventions to improve the detection, prevention, and treatment of ISH.https://doi.org/10.1186/s12872-022-02856-7Isolated systolic hypertensionOlder adultRisk factorPrevalenceIran
spellingShingle Ali Hosseinzadeh
Hossein Ebrahimi
Ahmad Khosravi
Mohammad Hassan Emamian
Hassan Hashemi
Akbar Fotouhi
Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study
BMC Cardiovascular Disorders
Isolated systolic hypertension
Older adult
Risk factor
Prevalence
Iran
title Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study
title_full Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study
title_fullStr Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study
title_full_unstemmed Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study
title_short Isolated systolic hypertension and its associated risk factors in Iranian middle age and older population: a population-based study
title_sort isolated systolic hypertension and its associated risk factors in iranian middle age and older population a population based study
topic Isolated systolic hypertension
Older adult
Risk factor
Prevalence
Iran
url https://doi.org/10.1186/s12872-022-02856-7
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