The pluripotent factor OCT4A enhances the self-renewal of human dental pulp stem cells by targeting lncRNA FTX in an LPS-induced inflammatory microenvironment

The pluripotent factor OCT4A enhances the self-renewal of human dental pulp stem cells by targeting lncRNA FTX in an LPS-induced inflammatory microenvironment

Abstract Background Regulating the pluripotency of human dental pulp stem cells (hDPSCs) is key for the self-repair of injured dental pulp. We previously found that OCT4A promotes the proliferation and odontogenic differentiation of human dental pulp cells (hDPCs). Recent studies have shown the inte...

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Bibliographic Details
Main Authors: Hong Hong, Kai Zeng, Can Zhou, Xiaochuan Chen, Zhezhen Xu, Mengjie Li, Lu Liu, Qian Zeng, Qian Tao, Xi Wei
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Stem Cell Research & Therapy
Subjects:
Dental pulp stem cells
OCT4A
LncRNA
FTX
Pulpitis
Online Access:https://doi.org/10.1186/s13287-023-03313-8

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