Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia
The hypoxia conditions in intensive farming systems generate oxidative stress related to oxidative damage and mortality of fish. Corn husk meal (CHM), as a source of antioxidants, might modulate the antioxidant response and prevent the damage elicited by hypoxia. This study evaluated CHM’s ability t...
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MDPI AG
2021-10-01
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| Series: | Molecules |
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| author | José Andrés Galeana-López Cynthia E. Lizárraga-Velázquez Crisantema Hernández Nayely Leyva-López J. Basilio Heredia |
| author_facet | José Andrés Galeana-López Cynthia E. Lizárraga-Velázquez Crisantema Hernández Nayely Leyva-López J. Basilio Heredia |
| author_sort | José Andrés Galeana-López |
| collection | DOAJ |
| description | The hypoxia conditions in intensive farming systems generate oxidative stress related to oxidative damage and mortality of fish. Corn husk meal (CHM), as a source of antioxidants, might modulate the antioxidant response and prevent the damage elicited by hypoxia. This study evaluated CHM’s ability to modulate a hepatic response in Nile tilapia exposed to hypoxia. A control and a test diet supplemented with 25 g CHM/kg feed were formulated. Ninety Nile tilapias (5.09 ± 0.55 g initial weight) were fed for 36 days to evaluate growth, feed efficiency, and hepatic antioxidant response (CAT, catalase; SOD, superoxide dismutase, and GPx, glutathione peroxidase) in normal oxygen conditions (normoxia). After the feeding trial (36 days), fish were exposed to hypoxia (1.5 ± 0.2 mg/L dissolved oxygen), and the hepatic antioxidant response was determined. There was no significant effect of CHM on growth and feed efficiency. The CAT activity was significantly increased in tilapias exposed to hypoxia and fed the test diet compared to the control group exposed to hypoxia. The SOD and GPx activities were unchanged in tilapias in normoxia and hypoxia conditions. Results suggest that CHM dietary supplementation promotes the antioxidant response in Nile tilapia exposed to hypoxia through CAT modulation. |
| first_indexed | 2024-03-10T06:21:08Z |
| format | Article |
| id | doaj.art-792f7a8d89404c66a61afda0dfafde94 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T06:21:08Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-792f7a8d89404c66a61afda0dfafde942023-11-22T19:19:00ZengMDPI AGMolecules1420-30492021-10-012620616110.3390/molecules26206161Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to HypoxiaJosé Andrés Galeana-López0Cynthia E. Lizárraga-Velázquez1Crisantema Hernández2Nayely Leyva-López3J. Basilio Heredia4Centro de Investigación en Alimentación y Desarrollo, A.C., Av. Sábalo Cerritos S/N, Mazatlán 82112, MexicoCentro de Investigación en Alimentación y Desarrollo, A.C., Av. Sábalo Cerritos S/N, Mazatlán 82112, MexicoCentro de Investigación en Alimentación y Desarrollo, A.C., Av. Sábalo Cerritos S/N, Mazatlán 82112, MexicoCentro de Investigación en Alimentación y Desarrollo, A.C., Av. Sábalo Cerritos S/N, Mazatlán 82112, MexicoCentro de Investigación en Alimentación y Desarrollo, A.C., Carretera a Eldorado Km. 5.5, Col. Campo El Diez, Culiacán 80110, MexicoThe hypoxia conditions in intensive farming systems generate oxidative stress related to oxidative damage and mortality of fish. Corn husk meal (CHM), as a source of antioxidants, might modulate the antioxidant response and prevent the damage elicited by hypoxia. This study evaluated CHM’s ability to modulate a hepatic response in Nile tilapia exposed to hypoxia. A control and a test diet supplemented with 25 g CHM/kg feed were formulated. Ninety Nile tilapias (5.09 ± 0.55 g initial weight) were fed for 36 days to evaluate growth, feed efficiency, and hepatic antioxidant response (CAT, catalase; SOD, superoxide dismutase, and GPx, glutathione peroxidase) in normal oxygen conditions (normoxia). After the feeding trial (36 days), fish were exposed to hypoxia (1.5 ± 0.2 mg/L dissolved oxygen), and the hepatic antioxidant response was determined. There was no significant effect of CHM on growth and feed efficiency. The CAT activity was significantly increased in tilapias exposed to hypoxia and fed the test diet compared to the control group exposed to hypoxia. The SOD and GPx activities were unchanged in tilapias in normoxia and hypoxia conditions. Results suggest that CHM dietary supplementation promotes the antioxidant response in Nile tilapia exposed to hypoxia through CAT modulation.https://www.mdpi.com/1420-3049/26/20/6161antioxidant enzymesphenolic compoundscorn by-product |
| spellingShingle | José Andrés Galeana-López Cynthia E. Lizárraga-Velázquez Crisantema Hernández Nayely Leyva-López J. Basilio Heredia Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia Molecules antioxidant enzymes phenolic compounds corn by-product |
| title | Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia |
| title_full | Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia |
| title_fullStr | Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia |
| title_full_unstemmed | Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia |
| title_short | Corn Husk Phenolics Modulate Hepatic Antioxidant Response in Nile Tilapia (<i>Oreochromis niloticus</i>) Exposed to Hypoxia |
| title_sort | corn husk phenolics modulate hepatic antioxidant response in nile tilapia i oreochromis niloticus i exposed to hypoxia |
| topic | antioxidant enzymes phenolic compounds corn by-product |
| url | https://www.mdpi.com/1420-3049/26/20/6161 |
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