Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study
Abstract Background Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medica...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-023-02849-6 |
| _version_ | 1797795650596765696 |
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| author | Yohei Iimura Mitsuko Nakazawa Yukari Tsuru Hitomi Togashi Tomoe Honda Keisuke Baba Masaaki Ishibashi Chieko Sasuga Naoki Furukawa Tomoko Sato Yasuo Matsubara Ayako Kamisato Eiko Yoshii Seiichiro Kuroda Narikazu Boku |
| author_facet | Yohei Iimura Mitsuko Nakazawa Yukari Tsuru Hitomi Togashi Tomoe Honda Keisuke Baba Masaaki Ishibashi Chieko Sasuga Naoki Furukawa Tomoko Sato Yasuo Matsubara Ayako Kamisato Eiko Yoshii Seiichiro Kuroda Narikazu Boku |
| author_sort | Yohei Iimura |
| collection | DOAJ |
| description | Abstract Background Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medical staff in our hospital and established clinical evidence of supportive care. This study aimed to prospectively evaluate the clinical activity and effect of MCST in patients with gastrointestinal cancer receiving chemotherapy. Methods This is a single-center, single-arm, observational study. Patients with gastrointestinal cancer scheduled to receive chemotherapy are enrolled and supported by the MCST. The primary endpoints are the number of interventions by medical staff and the number of patients who showed improvement in side effects. The secondary endpoints are the severity of side effects, medical expenses, number of consultations, the acceptance rate of prescription recommendations, adjuvant chemotherapy completion rates, dose intensity, and time required for co-medical intervention. In addition, medical staff and attending physicians evaluate all adverse events. Discussion This study is expected to contribute to establishing new cancer-supportive care teams for patients with gastrointestinal cancer receiving chemotherapy and those with cancer receiving chemotherapy. Trial registration This trial was registered in the Japan Registry of Clinical Trials (jRCT) as jRCT1030220495. The date of first registration, 29/11/2022, https://jrct.niph.go.jp/search |
| first_indexed | 2024-03-13T03:21:13Z |
| format | Article |
| id | doaj.art-793171316e844cadb3c6cec4138954ea |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-03-13T03:21:13Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-793171316e844cadb3c6cec4138954ea2023-06-25T11:18:57ZengBMCBMC Gastroenterology1471-230X2023-06-012311610.1186/s12876-023-02849-6Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST studyYohei Iimura0Mitsuko Nakazawa1Yukari Tsuru2Hitomi Togashi3Tomoe Honda4Keisuke Baba5Masaaki Ishibashi6Chieko Sasuga7Naoki Furukawa8Tomoko Sato9Yasuo Matsubara10Ayako Kamisato11Eiko Yoshii12Seiichiro Kuroda13Narikazu Boku14Department of Pharmacy, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Nursing, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Nursing, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Clinical Nutrition, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Clinical Nutrition, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Oncology and General Medicine, The Institute of Medical Science Hospital, The University of TokyoDepartment of Pharmacy, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Pharmacy, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Pharmacy, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Nursing, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Clinical Nutrition, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDivision of Bioethics, Advanced Clinical Research Center, The Institute of Medical Science, The University of TokyoDepartment of Nursing, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Pharmacy, The IMSUT Hospital, The Institute of Medical Science, The University of TokyoDepartment of Oncology and General Medicine, The Institute of Medical Science Hospital, The University of TokyoAbstract Background Although the multidisciplinary-collaborated team approach in cancer treatment has recently become popular, prospectively evaluated evidence is limited. We started a multidisciplinary-collaborated cancer support team (MCST) to facilitate cooperation across multidisciplinary medical staff in our hospital and established clinical evidence of supportive care. This study aimed to prospectively evaluate the clinical activity and effect of MCST in patients with gastrointestinal cancer receiving chemotherapy. Methods This is a single-center, single-arm, observational study. Patients with gastrointestinal cancer scheduled to receive chemotherapy are enrolled and supported by the MCST. The primary endpoints are the number of interventions by medical staff and the number of patients who showed improvement in side effects. The secondary endpoints are the severity of side effects, medical expenses, number of consultations, the acceptance rate of prescription recommendations, adjuvant chemotherapy completion rates, dose intensity, and time required for co-medical intervention. In addition, medical staff and attending physicians evaluate all adverse events. Discussion This study is expected to contribute to establishing new cancer-supportive care teams for patients with gastrointestinal cancer receiving chemotherapy and those with cancer receiving chemotherapy. Trial registration This trial was registered in the Japan Registry of Clinical Trials (jRCT) as jRCT1030220495. The date of first registration, 29/11/2022, https://jrct.niph.go.jp/searchhttps://doi.org/10.1186/s12876-023-02849-6Multidisciplinary-collaborated teamGastrointestinal cancerChemotherapySupportive care |
| spellingShingle | Yohei Iimura Mitsuko Nakazawa Yukari Tsuru Hitomi Togashi Tomoe Honda Keisuke Baba Masaaki Ishibashi Chieko Sasuga Naoki Furukawa Tomoko Sato Yasuo Matsubara Ayako Kamisato Eiko Yoshii Seiichiro Kuroda Narikazu Boku Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study BMC Gastroenterology Multidisciplinary-collaborated team Gastrointestinal cancer Chemotherapy Supportive care |
| title | Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study |
| title_full | Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study |
| title_fullStr | Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study |
| title_full_unstemmed | Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study |
| title_short | Evaluation of clinical effects of a multidisciplinary-collaborated cancer support team for gastrointestinal cancer chemotherapy: prospective observational study protocol of M-CAST study |
| title_sort | evaluation of clinical effects of a multidisciplinary collaborated cancer support team for gastrointestinal cancer chemotherapy prospective observational study protocol of m cast study |
| topic | Multidisciplinary-collaborated team Gastrointestinal cancer Chemotherapy Supportive care |
| url | https://doi.org/10.1186/s12876-023-02849-6 |
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