Intranasal Flunisolide Suppresses Pathological Alterations Caused by Silica Particles in the Lungs of Mice

Intranasal Flunisolide Suppresses Pathological Alterations Caused by Silica Particles in the Lungs of Mice

Silicosis is an occupational disease triggered by the inhalation of fine particles of crystalline silica and characterized by inflammation and scarring in the form of nodular lesions in the lungs. In spite of the therapeutic arsenal currently available, there is no specific treatment for the disease...

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Main Authors: Tatiana Paula Teixeira Ferreira, Januário Gomes Mourão e Lima, Francisco Alves Farias-Filho, Yago Amigo Pinho Jannini de Sá, Ana Carolina Santos de Arantes, Fernanda Verdini Guimarães, Vinicius de Frias Carvalho, Cory Hogaboam, John Wallace, Marco Aurélio Martins, Patrícia Machado Rodrigues e Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Endocrinology
Subjects:
lung
fibrosis
silica particles
therapy
flunisolide
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00388/full

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