Identification of a DRB3*011:01-restricted CD4+ T cell response against bovine respiratory syncytial virus fusion protein

Identification of a DRB3*011:01-restricted CD4+ T cell response against bovine respiratory syncytial virus fusion protein

Although Human Respiratory Syncytial Virus (HRSV) is a significant cause of severe respiratory disease with high morbidity and mortality in pediatric and elderly populations worldwide there is no licensed vaccine. Bovine Respiratory Syncytial Virus (BRSV) is a closely related orthopneumovirus with s...

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Bibliographic Details
Main Authors: Bryan S. Kaplan, Amelia R. Hofstetter, Jodi L. McGill, John D. Lippolis, Junzo Norimine, Rohana P. Dassanayake, Randy E. Sacco
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Immunology
Subjects:
BRSV
F protein
BoLA class II
T cell
antigen presentation
cattle
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1040075/full

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