Angiotensin-Converting Enzyme Gene I/D Polymorphism Is Associated With Systemic Lupus Erythematosus Susceptibility: An Updated Meta-Analysis and Trial Sequential Analysis

Angiotensin-Converting Enzyme Gene I/D Polymorphism Is Associated With Systemic Lupus Erythematosus Susceptibility: An Updated Meta-Analysis and Trial Sequential Analysis

Angiotensin-converting enzyme (ACE) gene is indispensable for endothelial control and vascular tone regulatory systems, usually affected in Systemic Lupus Erythematosus (SLE). ACE insertion/deletion (I/D) polymorphism may influence the progress of SLE. Earlier studies have investigated this associat...

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Bibliographic Details
Main Authors: Saif Khan, Sajad A. Dar, Raju K. Mandal, Arshad Jawed, Mohd Wahid, Aditya K. Panda, Mohtashim Lohani, B. N. Mishra, Naseem Akhter, Shafiul Haque
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Physiology
Subjects:
genetic variants
polymorphism
ACE gene
meta-analysis
genotypic risk
SLE
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01793/full

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