Targeted therapy for HCC using dumbbell-like nanoparticles conjugated to monoclonal antibodies against VEGF and cancer stem cell receptors in mice

Targeted therapy for HCC using dumbbell-like nanoparticles conjugated to monoclonal antibodies against VEGF and cancer stem cell receptors in mice

Abstract Background Hepatocellular carcinoma (HCC) is the leading cause of death worldwide. Nanoparticles allow early detection of tumor and delivery of chemotherapeutic drugs to the specific tumor site. This study aimed to assess the therapeutic role of dumbbell-like nanoparticles conjugated with m...

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Bibliographic Details
Main Authors: Wafaa Mansour, Shahira Fathy EL Fedawy, Shimaa Attia Atta, Rewan Mohsen Zarie, Nermeen Tayseer Aly Fouad, Sara Maher, Taghreed M. Hussein, Doaa Mohamed Abdel Aziz, Manal Kamel
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Cancer Nanotechnology
Subjects:
Hepatocellular carcinoma
Nanoparticles
Avastin
CD90
Online Access:https://doi.org/10.1186/s12645-023-00163-0

Internet

https://doi.org/10.1186/s12645-023-00163-0

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