Water mediated oxalic acid catalyzed one pot synthesis of 1,8-dioxodecahydroacridines

A simple and convenient one step method for synthesis of acridines and its derivatives from condensation of aromatic aldehydes, cyclic diketones, aryl amines or ammonium acetates using water as a reaction medium is reported. The present protocol provides several advantages such as good yields, cheap...

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Bibliographic Details
Main Authors: Jaiprakash N. Sangshetti, Priyanka P. Dharmadhikari, Rashmi S. Chouthe, Bibi Fatema
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212001438
Description
Summary:A simple and convenient one step method for synthesis of acridines and its derivatives from condensation of aromatic aldehydes, cyclic diketones, aryl amines or ammonium acetates using water as a reaction medium is reported. The present protocol provides several advantages such as good yields, cheap catalyst, short reaction time, easy work-up, simplicity in operation. The use of environmentally benign water as a solvent supports the green aspect of method.
ISSN:1878-5352