Prevalence of intolerance to salicylates in patients with nasal polyposis
Background: Salicylates intolerance is related to alteration in the metabolism of arachidonic acid leading to increased leukotrienes. The condition may be manifested with respiratory, skin or systemic symptoms or associated with sinonasal polyposis. Salicylates are present in anti-inflammatory drugs...
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| Format: | Article |
| Language: | English |
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Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2015-06-01
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| Series: | Revista Alergia México |
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| Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/101 |
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| author | Jaisel Luz Castilla-Rodríguez María Eugenia Vargas-Camaño Rodrigo Alberto Rodríguez-Briceño Jorge Galicia-Tapia María Isabel Castrejón-Vázquez |
| author_facet | Jaisel Luz Castilla-Rodríguez María Eugenia Vargas-Camaño Rodrigo Alberto Rodríguez-Briceño Jorge Galicia-Tapia María Isabel Castrejón-Vázquez |
| author_sort | Jaisel Luz Castilla-Rodríguez |
| collection | DOAJ |
| description | Background: Salicylates intolerance is related to alteration in the metabolism of arachidonic acid leading to increased leukotrienes. The condition may be manifested with respiratory, skin or systemic symptoms or associated with sinonasal polyposis. Salicylates are present in anti-inflammatory drugs, cosmetics products and food.
Objective: To determine the prevalence of salicylates intolerance in patients with sinonasal polyposis presenting to Clinical Immunology and Allergy and Otolaryngology Service, CMN 20 Noviembre, Mexico City.
Material and method: An observational, descriptive, cross sectional study included patients with sinonasal polyposis. The sample size was 49 patients, and variables were compared using STATISTICA 8.0.
Results: The prevalence of sinonasal polyposis was 4% of the study group, predominantly in females; only 24% of the population had an ideal weight, the salicylates intolerance prevalence was 53%, and the Samter triad was 31%.
Conclusions: Sinonasal polyposis has an inflammatory disease pattern. Its pathophysiology is not yet fully established and in this study was related to obesity and persistent sinusitis. The most feared complication recurrence is associated with salicylates intolerance. The study found a slight increase of recurrence in the group of intolerance, with no statistically significant difference, possibly related to the sample size. |
| first_indexed | 2024-03-12T06:44:17Z |
| format | Article |
| id | doaj.art-79423d54dd8c45ccb2bcd93baa5d39b4 |
| institution | Directory Open Access Journal |
| issn | 0002-5151 2448-9190 |
| language | English |
| last_indexed | 2024-03-12T06:44:17Z |
| publishDate | 2015-06-01 |
| publisher | Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
| record_format | Article |
| series | Revista Alergia México |
| spelling | doaj.art-79423d54dd8c45ccb2bcd93baa5d39b42023-09-03T00:43:28ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902015-06-0162320221010.29262/ram.v62i3.10191Prevalence of intolerance to salicylates in patients with nasal polyposisJaisel Luz Castilla-Rodríguez0María Eugenia Vargas-Camaño1Rodrigo Alberto Rodríguez-Briceño2Jorge Galicia-Tapia3María Isabel Castrejón-Vázquez4Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Servicio Inmunología Clínica y Alergia, Ciudad de MéxicoInstituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Servicio Inmunología Clínica y Alergia, Ciudad de MéxicoInstituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Servicio Inmunología Clínica y Alergia, Ciudad de MéxicoInstituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Servicio Inmunología Clínica y Alergia, Ciudad de MéxicoInstituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Centro Médico Nacional 20 de Noviembre, Servicio Inmunología Clínica y Alergia, Ciudad de MéxicoBackground: Salicylates intolerance is related to alteration in the metabolism of arachidonic acid leading to increased leukotrienes. The condition may be manifested with respiratory, skin or systemic symptoms or associated with sinonasal polyposis. Salicylates are present in anti-inflammatory drugs, cosmetics products and food. Objective: To determine the prevalence of salicylates intolerance in patients with sinonasal polyposis presenting to Clinical Immunology and Allergy and Otolaryngology Service, CMN 20 Noviembre, Mexico City. Material and method: An observational, descriptive, cross sectional study included patients with sinonasal polyposis. The sample size was 49 patients, and variables were compared using STATISTICA 8.0. Results: The prevalence of sinonasal polyposis was 4% of the study group, predominantly in females; only 24% of the population had an ideal weight, the salicylates intolerance prevalence was 53%, and the Samter triad was 31%. Conclusions: Sinonasal polyposis has an inflammatory disease pattern. Its pathophysiology is not yet fully established and in this study was related to obesity and persistent sinusitis. The most feared complication recurrence is associated with salicylates intolerance. The study found a slight increase of recurrence in the group of intolerance, with no statistically significant difference, possibly related to the sample size.http://revistaalergia.mx/ojs/index.php/ram/article/view/101intolerancia salicilatospoliposis nasosinusal |
| spellingShingle | Jaisel Luz Castilla-Rodríguez María Eugenia Vargas-Camaño Rodrigo Alberto Rodríguez-Briceño Jorge Galicia-Tapia María Isabel Castrejón-Vázquez Prevalence of intolerance to salicylates in patients with nasal polyposis Revista Alergia México intolerancia salicilatos poliposis nasosinusal |
| title | Prevalence of intolerance to salicylates in patients with nasal polyposis |
| title_full | Prevalence of intolerance to salicylates in patients with nasal polyposis |
| title_fullStr | Prevalence of intolerance to salicylates in patients with nasal polyposis |
| title_full_unstemmed | Prevalence of intolerance to salicylates in patients with nasal polyposis |
| title_short | Prevalence of intolerance to salicylates in patients with nasal polyposis |
| title_sort | prevalence of intolerance to salicylates in patients with nasal polyposis |
| topic | intolerancia salicilatos poliposis nasosinusal |
| url | http://revistaalergia.mx/ojs/index.php/ram/article/view/101 |
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