Parvovirus minute virus of mice interacts with sites of cellular DNA damage to establish and amplify its lytic infection

Parvovirus minute virus of mice interacts with sites of cellular DNA damage to establish and amplify its lytic infection

We have developed a generally adaptable, novel high-throughput Viral Chromosome Conformation Capture assay (V3C-seq) for use in trans that allows genome-wide identification of the direct interactions of a lytic virus genome with distinct regions of the cellular chromosome. Upon infection, we found t...

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Bibliographic Details
Main Authors: Kinjal Majumder, Juexin Wang, Maria Boftsi, Matthew S Fuller, Jordan E Rede, Trupti Joshi, David J Pintel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
Parvovirus
DNA damage response
chromosome conformation capture
topologically associating domains
Online Access:https://elifesciences.org/articles/37750

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