Marine Natural Products from Tunicates and Their Associated Microbes
Marine tunicates are identified as a potential source of marine natural products (MNPs), demonstrating a wide range of biological properties, like antimicrobial and anticancer activities. The symbiotic relationship between tunicates and specific microbial groups has revealed the acquisition of micro...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-05-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/19/6/308 |
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| author | Chatragadda Ramesh Bhushan Rao Tulasi Mohanraju Raju Narsinh Thakur Laurent Dufossé |
| author_facet | Chatragadda Ramesh Bhushan Rao Tulasi Mohanraju Raju Narsinh Thakur Laurent Dufossé |
| author_sort | Chatragadda Ramesh |
| collection | DOAJ |
| description | Marine tunicates are identified as a potential source of marine natural products (MNPs), demonstrating a wide range of biological properties, like antimicrobial and anticancer activities. The symbiotic relationship between tunicates and specific microbial groups has revealed the acquisition of microbial compounds by tunicates for defensive purpose. For instance, yellow pigmented compounds, “tambjamines”, produced by the tunicate, <i>Sigillina signifera</i> (Sluiter, 1909), primarily originated from their bacterial symbionts, which are involved in their chemical defense function, indicating the ecological role of symbiotic microbial association with tunicates. This review has garnered comprehensive literature on MNPs produced by tunicates and their symbiotic microbionts. Various sections covered in this review include tunicates’ ecological functions, biological activities, such as antimicrobial, antitumor, and anticancer activities, metabolic origins, utilization of invasive tunicates, and research gaps. Apart from the literature content, 20 different chemical databases were explored to identify tunicates-derived MNPs. In addition, the management and exploitation of tunicate resources in the global oceans are detailed for their ecological and biotechnological implications. |
| first_indexed | 2024-03-10T11:01:32Z |
| format | Article |
| id | doaj.art-79446f538b9a436292516a54a16e9a4d |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-10T11:01:32Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-79446f538b9a436292516a54a16e9a4d2023-11-21T21:29:57ZengMDPI AGMarine Drugs1660-33972021-05-0119630810.3390/md19060308Marine Natural Products from Tunicates and Their Associated MicrobesChatragadda Ramesh0Bhushan Rao Tulasi1Mohanraju Raju2Narsinh Thakur3Laurent Dufossé4Biological Oceanography Division (BOD), CSIR-National Institute of Oceanography (CSIR-NIO), Dona Paula 403004, IndiaZoology Division, Sri Gurajada Appa Rao Government Degree College, Yellamanchili 531055, IndiaDepartment of Ocean Studies and Marine Biology, Pondicherry Central University, Brookshabad Campus, Port Blair 744102, IndiaChemical Oceanography Division (COD), CSIR-National Institute of Oceanography (CSIR-NIO), Dona Paula 403004, IndiaLaboratoire de Chimie et Biotechnologie des Produits Naturels (CHEMBIOPRO), Université de La Réunion, ESIROI Agroalimentaire, 15 Avenue René Cassin, CS 92003, CEDEX 9, F-97744 Saint-Denis, Ile de La Réunion, FranceMarine tunicates are identified as a potential source of marine natural products (MNPs), demonstrating a wide range of biological properties, like antimicrobial and anticancer activities. The symbiotic relationship between tunicates and specific microbial groups has revealed the acquisition of microbial compounds by tunicates for defensive purpose. For instance, yellow pigmented compounds, “tambjamines”, produced by the tunicate, <i>Sigillina signifera</i> (Sluiter, 1909), primarily originated from their bacterial symbionts, which are involved in their chemical defense function, indicating the ecological role of symbiotic microbial association with tunicates. This review has garnered comprehensive literature on MNPs produced by tunicates and their symbiotic microbionts. Various sections covered in this review include tunicates’ ecological functions, biological activities, such as antimicrobial, antitumor, and anticancer activities, metabolic origins, utilization of invasive tunicates, and research gaps. Apart from the literature content, 20 different chemical databases were explored to identify tunicates-derived MNPs. In addition, the management and exploitation of tunicate resources in the global oceans are detailed for their ecological and biotechnological implications.https://www.mdpi.com/1660-3397/19/6/308tunicatessymbiotic microbespigmentsbioactive compoundsalkaloids &peptides |
| spellingShingle | Chatragadda Ramesh Bhushan Rao Tulasi Mohanraju Raju Narsinh Thakur Laurent Dufossé Marine Natural Products from Tunicates and Their Associated Microbes Marine Drugs tunicates symbiotic microbes pigments bioactive compounds alkaloids & peptides |
| title | Marine Natural Products from Tunicates and Their Associated Microbes |
| title_full | Marine Natural Products from Tunicates and Their Associated Microbes |
| title_fullStr | Marine Natural Products from Tunicates and Their Associated Microbes |
| title_full_unstemmed | Marine Natural Products from Tunicates and Their Associated Microbes |
| title_short | Marine Natural Products from Tunicates and Their Associated Microbes |
| title_sort | marine natural products from tunicates and their associated microbes |
| topic | tunicates symbiotic microbes pigments bioactive compounds alkaloids & peptides |
| url | https://www.mdpi.com/1660-3397/19/6/308 |
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