Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study
Abstract Background Fatigue is one of the most common symptoms reported by patients with ulcerative colitis (UC), while it has not been fully recognized and taken seriously in clinical practice. We aimed to investigate the prevalence of fatigue in patients with UC and identify the factors associated...
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| Format: | Article |
| Language: | English |
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BMC
2022-06-01
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| Series: | BMC Gastroenterology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12876-022-02357-z |
| _version_ | 1811243512889344000 |
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| author | Feng Xu Jingyi Hu Qian Yang Yuejin Ji Cheng Cheng Lei Zhu Hong Shen |
| author_facet | Feng Xu Jingyi Hu Qian Yang Yuejin Ji Cheng Cheng Lei Zhu Hong Shen |
| author_sort | Feng Xu |
| collection | DOAJ |
| description | Abstract Background Fatigue is one of the most common symptoms reported by patients with ulcerative colitis (UC), while it has not been fully recognized and taken seriously in clinical practice. We aimed to investigate the prevalence of fatigue in patients with UC and identify the factors associated with fatigue and its severity in China. Methods A cross-sectional study was conducted in Affiliated Hospital of Nanjing University of Chinese Medicine from May 2020 to February 2021. Demographic and clinical characteristics were collected. Fatigue was evaluated with the Fatigue Severity Scale and the Multidimensional Fatigue Inventory. The Hospital Anxiety and Depression Scale, the Pittsburgh Sleep Index Scale and the Malnutrition Universal Screening Tool were respectively used to evaluate the anxiety, depression, sleep disturbance and nutritional risk of patients with UC. Results A total of 220 UC patients were enrolled in this study. The prevalence of fatigue in patients was 61.8%, of which in patients with disease activity was 68.2%, and in patients in remission was 40.0%. Univariate analysis indicated that the Montreal classification, disease activity, anemia, anxiety, depression, sleep disturbance and high nutritional risk were the factors associated with fatigue in Patients with UC. Multivariate logistic regression analysis showed that the Montreal classification (E3: E1, OR = 2.665, 95% CI = 1.134–6.216), disease activity (OR = 2.157, 95% CI = 1.055–4.410) and anxiety (OR = 2.867, 95% CI = 1.154–7.126) were related to an increased risk of fatigue. Disease activity (RC = 0.240, 95% CI = 0.193–0.674) and anxiety (RC = 0.181, 95% CI = 0.000–0.151) were associated with severity of fatigue. Conclusions This study demonstrated that the prevalence of fatigue among UC patients in China. The Montreal classification, disease activity and anxiety are associated with an increased risk of fatigue. |
| first_indexed | 2024-04-12T14:09:47Z |
| format | Article |
| id | doaj.art-79475222a5e848ff8e145f0b3ccea6be |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-04-12T14:09:47Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-79475222a5e848ff8e145f0b3ccea6be2022-12-22T03:29:56ZengBMCBMC Gastroenterology1471-230X2022-06-012211910.1186/s12876-022-02357-zPrevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional studyFeng Xu0Jingyi Hu1Qian Yang2Yuejin Ji3Cheng Cheng4Lei Zhu5Hong Shen6Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Affiliated Hospital of Nanjing University of Chinese Medicine (Jiangsu Province Hospital of Chinese Medicine)Abstract Background Fatigue is one of the most common symptoms reported by patients with ulcerative colitis (UC), while it has not been fully recognized and taken seriously in clinical practice. We aimed to investigate the prevalence of fatigue in patients with UC and identify the factors associated with fatigue and its severity in China. Methods A cross-sectional study was conducted in Affiliated Hospital of Nanjing University of Chinese Medicine from May 2020 to February 2021. Demographic and clinical characteristics were collected. Fatigue was evaluated with the Fatigue Severity Scale and the Multidimensional Fatigue Inventory. The Hospital Anxiety and Depression Scale, the Pittsburgh Sleep Index Scale and the Malnutrition Universal Screening Tool were respectively used to evaluate the anxiety, depression, sleep disturbance and nutritional risk of patients with UC. Results A total of 220 UC patients were enrolled in this study. The prevalence of fatigue in patients was 61.8%, of which in patients with disease activity was 68.2%, and in patients in remission was 40.0%. Univariate analysis indicated that the Montreal classification, disease activity, anemia, anxiety, depression, sleep disturbance and high nutritional risk were the factors associated with fatigue in Patients with UC. Multivariate logistic regression analysis showed that the Montreal classification (E3: E1, OR = 2.665, 95% CI = 1.134–6.216), disease activity (OR = 2.157, 95% CI = 1.055–4.410) and anxiety (OR = 2.867, 95% CI = 1.154–7.126) were related to an increased risk of fatigue. Disease activity (RC = 0.240, 95% CI = 0.193–0.674) and anxiety (RC = 0.181, 95% CI = 0.000–0.151) were associated with severity of fatigue. Conclusions This study demonstrated that the prevalence of fatigue among UC patients in China. The Montreal classification, disease activity and anxiety are associated with an increased risk of fatigue.https://doi.org/10.1186/s12876-022-02357-zUlcerative colitisFatigueRisk factorsDisease activityChina |
| spellingShingle | Feng Xu Jingyi Hu Qian Yang Yuejin Ji Cheng Cheng Lei Zhu Hong Shen Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study BMC Gastroenterology Ulcerative colitis Fatigue Risk factors Disease activity China |
| title | Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study |
| title_full | Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study |
| title_fullStr | Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study |
| title_full_unstemmed | Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study |
| title_short | Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study |
| title_sort | prevalence and factors associated with fatigue in patients with ulcerative colitis in china a cross sectional study |
| topic | Ulcerative colitis Fatigue Risk factors Disease activity China |
| url | https://doi.org/10.1186/s12876-022-02357-z |
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