Research progress on STAT3 and pathogenesis of Parkinson's disease
Parkinson's disease (PD) is a chronic progressive neurodegenerative disease. Signal transducer and activator of transcription 3 (STAT3) is involved in the development and progression of PD, oxidative stress, neuro-inflammatory response, abnormal α-synuclein aggregation, mitochondrial dysfunctio...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2022-12-01
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| Series: | Jichu yixue yu linchuang |
| Subjects: | |
| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-12-1935.pdf |
| _version_ | 1827390593546846208 |
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| author | WU Chang-bao, HAO Yan-lei |
| author_facet | WU Chang-bao, HAO Yan-lei |
| author_sort | WU Chang-bao, HAO Yan-lei |
| collection | DOAJ |
| description | Parkinson's disease (PD) is a chronic progressive neurodegenerative disease. Signal transducer and activator of transcription 3 (STAT3) is involved in the development and progression of PD, oxidative stress, neuro-inflammatory response, abnormal α-synuclein aggregation, mitochondrial dysfunction and iron death, so they are expected to be a new therapeutic targets and provide new research ideas for the treatment of PD. |
| first_indexed | 2024-03-08T16:54:59Z |
| format | Article |
| id | doaj.art-7947ad00f5b34c0dab1964c8912cec00 |
| institution | Directory Open Access Journal |
| issn | 1001-6325 |
| language | zho |
| last_indexed | 2024-03-08T16:54:59Z |
| publishDate | 2022-12-01 |
| publisher | Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. |
| record_format | Article |
| series | Jichu yixue yu linchuang |
| spelling | doaj.art-7947ad00f5b34c0dab1964c8912cec002024-01-05T02:36:47ZzhoInstitute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.Jichu yixue yu linchuang1001-63252022-12-0142121935193810.16352/j.issn.1001-6325.2022.12.1935Research progress on STAT3 and pathogenesis of Parkinson's diseaseWU Chang-bao, HAO Yan-lei01. Medical College of Jining Medical University, Jining 272029; ;2. Department of Neurology, Affiliated Hospital of Jining Medical University, Jining 272029, ChinaParkinson's disease (PD) is a chronic progressive neurodegenerative disease. Signal transducer and activator of transcription 3 (STAT3) is involved in the development and progression of PD, oxidative stress, neuro-inflammatory response, abnormal α-synuclein aggregation, mitochondrial dysfunction and iron death, so they are expected to be a new therapeutic targets and provide new research ideas for the treatment of PD.http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-12-1935.pdfstat3 transcription factor|parkinson's disease|pathogenesis |
| spellingShingle | WU Chang-bao, HAO Yan-lei Research progress on STAT3 and pathogenesis of Parkinson's disease Jichu yixue yu linchuang stat3 transcription factor|parkinson's disease|pathogenesis |
| title | Research progress on STAT3 and pathogenesis of Parkinson's disease |
| title_full | Research progress on STAT3 and pathogenesis of Parkinson's disease |
| title_fullStr | Research progress on STAT3 and pathogenesis of Parkinson's disease |
| title_full_unstemmed | Research progress on STAT3 and pathogenesis of Parkinson's disease |
| title_short | Research progress on STAT3 and pathogenesis of Parkinson's disease |
| title_sort | research progress on stat3 and pathogenesis of parkinson s disease |
| topic | stat3 transcription factor|parkinson's disease|pathogenesis |
| url | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-12-1935.pdf |
| work_keys_str_mv | AT wuchangbaohaoyanlei researchprogressonstat3andpathogenesisofparkinsonsdisease |