Acute myocardial infarction risk factors at radiation-dangerous workplaces
Aim. To study risk factors (RF) of acute myocardial infarction (AMI), their significance and interplay in a “closed” population – people with chronic low-dose ionizing radiation (IR) exposure at their workplace. Material and methods. According to WHO AMI Registry, 1 370 AMI cases were analyzed, incl...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2005-06-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/948 |
| _version_ | 1797882813305847808 |
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| author | Yu. V. Semenova A. B. Karpov T. M. Litvinenko R. M. Takhauov V. P. Leonov |
| author_facet | Yu. V. Semenova A. B. Karpov T. M. Litvinenko R. M. Takhauov V. P. Leonov |
| author_sort | Yu. V. Semenova |
| collection | DOAJ |
| description | Aim. To study risk factors (RF) of acute myocardial infarction (AMI), their significance and interplay in a “closed” population – people with chronic low-dose ionizing radiation (IR) exposure at their workplace. Material and methods. According to WHO AMI Registry, 1 370 AMI cases were analyzed, including 327 cases in people exposed to long-term low-dose IR at their workplace. A prospective cohort study of AMI morbidity in a “closed” population (1998-2002) was performed. Results. It was demonstrated that total dose of external radiation, duration of working in radiation-dangerous environment, and traditional cardiovascular RF, were independently distributed in IR-exposed AMI patients. Maximal total doses of external radiation were registered in young AMI patients. Individual dose negatively correlated with arterial hypertension (AH) duration before AMI development. Conclusion. Among persons with long-term IR exposure, psycho-emotional stress, smoking, and AH were the leading cardiovascular RF in AMI pathogenesis. Long-term, low-dose IR enhanced traditional cardiovascular RF (dyslipidemia, AH) aggression in AMI pathogenesis. |
| first_indexed | 2024-04-10T03:40:35Z |
| format | Article |
| id | doaj.art-794828eaf39743ab93d975ee58c3367c |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2024-04-10T03:40:35Z |
| publishDate | 2005-06-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-794828eaf39743ab93d975ee58c3367c2023-03-13T07:23:11Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252005-06-0143, ч.II4449663Acute myocardial infarction risk factors at radiation-dangerous workplacesYu. V. Semenova0A. B. Karpov1T. M. Litvinenko2R. M. Takhauov3V. P. Leonov4Северский биофизический научный центр Федерального управления «Медбиоэкстрем», г.СеверскСеверский биофизический научный центр Федерального управления «Медбиоэкстрем», г.Северск; Проблемная научно-исследовательская лаборатория «Радиационная медицина и радиобиология» СО РАМН, г.СеверскСеверский биофизический научный центр Федерального управления «Медбиоэкстрем», г.СеверскСеверский биофизический научный центр Федерального управления «Медбиоэкстрем», г.Северск; Проблемная научно-исследовательская лаборатория «Радиационная медицина и радиобиология» СО РАМН, г.СеверскТомский Государственный университет, г.ТомскAim. To study risk factors (RF) of acute myocardial infarction (AMI), their significance and interplay in a “closed” population – people with chronic low-dose ionizing radiation (IR) exposure at their workplace. Material and methods. According to WHO AMI Registry, 1 370 AMI cases were analyzed, including 327 cases in people exposed to long-term low-dose IR at their workplace. A prospective cohort study of AMI morbidity in a “closed” population (1998-2002) was performed. Results. It was demonstrated that total dose of external radiation, duration of working in radiation-dangerous environment, and traditional cardiovascular RF, were independently distributed in IR-exposed AMI patients. Maximal total doses of external radiation were registered in young AMI patients. Individual dose negatively correlated with arterial hypertension (AH) duration before AMI development. Conclusion. Among persons with long-term IR exposure, psycho-emotional stress, smoking, and AH were the leading cardiovascular RF in AMI pathogenesis. Long-term, low-dose IR enhanced traditional cardiovascular RF (dyslipidemia, AH) aggression in AMI pathogenesis.https://cardiovascular.elpub.ru/jour/article/view/948острый инфаркт миокардазаболеваемостьфакторы риска«малые» дозы ионизирующего излучения |
| spellingShingle | Yu. V. Semenova A. B. Karpov T. M. Litvinenko R. M. Takhauov V. P. Leonov Acute myocardial infarction risk factors at radiation-dangerous workplaces Кардиоваскулярная терапия и профилактика острый инфаркт миокарда заболеваемость факторы риска «малые» дозы ионизирующего излучения |
| title | Acute myocardial infarction risk factors at radiation-dangerous workplaces |
| title_full | Acute myocardial infarction risk factors at radiation-dangerous workplaces |
| title_fullStr | Acute myocardial infarction risk factors at radiation-dangerous workplaces |
| title_full_unstemmed | Acute myocardial infarction risk factors at radiation-dangerous workplaces |
| title_short | Acute myocardial infarction risk factors at radiation-dangerous workplaces |
| title_sort | acute myocardial infarction risk factors at radiation dangerous workplaces |
| topic | острый инфаркт миокарда заболеваемость факторы риска «малые» дозы ионизирующего излучения |
| url | https://cardiovascular.elpub.ru/jour/article/view/948 |
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