Reducing research waste by promoting informed responses to invitations to participate in clinical trials
Abstract Poor recruitment to, and retention in, clinical trials is a source of research waste that could be reduced by more informed choices about participation. Barriers to effective recruitment and retention can be wide-ranging but relevance of the questions being addressed by trials and the outco...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-10-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-019-3704-x |
| _version_ | 1819229517966737408 |
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| author | Katie Gillies Iain Chalmers Paul Glasziou Diana Elbourne Jim Elliott Shaun Treweek |
| author_facet | Katie Gillies Iain Chalmers Paul Glasziou Diana Elbourne Jim Elliott Shaun Treweek |
| author_sort | Katie Gillies |
| collection | DOAJ |
| description | Abstract Poor recruitment to, and retention in, clinical trials is a source of research waste that could be reduced by more informed choices about participation. Barriers to effective recruitment and retention can be wide-ranging but relevance of the questions being addressed by trials and the outcomes that they are assessing are key for potential participants. Decisions about trial participation should be informed by general and trial-specific information and by considering broader assessments of ‘informedness’ and how they impact on both recruitment and retention. We suggest that more informed decisions about trial participation should encourage personally appropriate decisions, increase recruitment and retention, and reduce research waste and increase its value. |
| first_indexed | 2024-12-23T11:14:26Z |
| format | Article |
| id | doaj.art-794df4c9a60d4026be7a841fa79d3418 |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-23T11:14:26Z |
| publishDate | 2019-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-794df4c9a60d4026be7a841fa79d34182022-12-21T17:49:15ZengBMCTrials1745-62152019-10-012011410.1186/s13063-019-3704-xReducing research waste by promoting informed responses to invitations to participate in clinical trialsKatie Gillies0Iain Chalmers1Paul Glasziou2Diana Elbourne3Jim Elliott4Shaun Treweek5Health Services Research Unit, University of AberdeenCentre for Evidence-Based Medicine, University of OxfordBond UniversityLondon School of Hygiene and Tropical MedicineHealth Research AuthorityHealth Services Research Unit, University of AberdeenAbstract Poor recruitment to, and retention in, clinical trials is a source of research waste that could be reduced by more informed choices about participation. Barriers to effective recruitment and retention can be wide-ranging but relevance of the questions being addressed by trials and the outcomes that they are assessing are key for potential participants. Decisions about trial participation should be informed by general and trial-specific information and by considering broader assessments of ‘informedness’ and how they impact on both recruitment and retention. We suggest that more informed decisions about trial participation should encourage personally appropriate decisions, increase recruitment and retention, and reduce research waste and increase its value.http://link.springer.com/article/10.1186/s13063-019-3704-xRecruitmentRetentionClinical trialsResearch wasteInformed choice |
| spellingShingle | Katie Gillies Iain Chalmers Paul Glasziou Diana Elbourne Jim Elliott Shaun Treweek Reducing research waste by promoting informed responses to invitations to participate in clinical trials Trials Recruitment Retention Clinical trials Research waste Informed choice |
| title | Reducing research waste by promoting informed responses to invitations to participate in clinical trials |
| title_full | Reducing research waste by promoting informed responses to invitations to participate in clinical trials |
| title_fullStr | Reducing research waste by promoting informed responses to invitations to participate in clinical trials |
| title_full_unstemmed | Reducing research waste by promoting informed responses to invitations to participate in clinical trials |
| title_short | Reducing research waste by promoting informed responses to invitations to participate in clinical trials |
| title_sort | reducing research waste by promoting informed responses to invitations to participate in clinical trials |
| topic | Recruitment Retention Clinical trials Research waste Informed choice |
| url | http://link.springer.com/article/10.1186/s13063-019-3704-x |
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