LTD is involved in the formation and maintenance of rat hippocampal CA1 place-cell fields
LTP and LTD are involved in shaping hippocampal place field representations. Here, the authors show that de novo pathway-specific hippocampal LTD changes dynamics and stability of newly formed place fields, regulating acquisition and maintenance of novel spatial information in adult rats.
Main Authors: | Donovan M. Ashby, Stan B. Floresco, Anthony G. Phillips, Alexander McGirr, Jeremy K. Seamans, Yu Tian Wang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-01-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-20317-7 |
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