Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review
Objective: Intravenous/intravascular leiomyomatosis is characterized by intravenous proliferation of a histologically benign smooth muscle cell tumor mass that is non-tissue-invasive. Although benign, intravenous leiomyomatosis may cause remarkable systematic complications, presents significant diag...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2017-06-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455917300876 |
| _version_ | 1819327112069251072 |
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| author | Hui-Ying Low Yu Zhao Kuo-Shu Huang Huang-Pin Shen Pei-Ju Wu Chih-Jen Tseng |
| author_facet | Hui-Ying Low Yu Zhao Kuo-Shu Huang Huang-Pin Shen Pei-Ju Wu Chih-Jen Tseng |
| author_sort | Hui-Ying Low |
| collection | DOAJ |
| description | Objective: Intravenous/intravascular leiomyomatosis is characterized by intravenous proliferation of a histologically benign smooth muscle cell tumor mass that is non-tissue-invasive. Although benign, intravenous leiomyomatosis may cause remarkable systematic complications, presents significant diagnostic difficulties, and also is characterized by a relatively increased possibility of recurrence. We determine patients’ characteristics, and recurrence and treatment of intravenous leiomyomatosis.
Materials and methods: Prognostic factors are analyzed with univariate analysis. Differences in categorical data are evaluated by the X2 test. A P value below 0.05 is regarded as indicating a significant difference.
Results: The data results accord with the widely held view that complete excision of intravenous leiomyomata achieves favorable prognoses regarding remission. The efficacy of using Gonadotropin releasing hormone agonists to prevent growth or recurrence of tumors in unresected or incompletely resected intravenous leiomyomatosis foci.
Conclusion: If complete surgical resection is not possible, partial resection followed by hormone therapy using gonadotropin-releasing hormone agonists is recommended, which in this study achieved the same favorable prognosis with regard to remission. |
| first_indexed | 2024-12-24T13:05:39Z |
| format | Article |
| id | doaj.art-7958e2030be84880bd3427bfb5276843 |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-24T13:05:39Z |
| publishDate | 2017-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-7958e2030be84880bd3427bfb52768432022-12-21T16:54:00ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592017-06-0156336236510.1016/j.tjog.2017.04.017Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature reviewHui-Ying Low0Yu Zhao1Kuo-Shu Huang2Huang-Pin Shen3Pei-Ju Wu4Chih-Jen Tseng5Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Gynecology and Obstetrics, Second Affiliated Hospital of Wenzhou Medical University, ChinaChung Shan Medical University, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, TaiwanObjective: Intravenous/intravascular leiomyomatosis is characterized by intravenous proliferation of a histologically benign smooth muscle cell tumor mass that is non-tissue-invasive. Although benign, intravenous leiomyomatosis may cause remarkable systematic complications, presents significant diagnostic difficulties, and also is characterized by a relatively increased possibility of recurrence. We determine patients’ characteristics, and recurrence and treatment of intravenous leiomyomatosis. Materials and methods: Prognostic factors are analyzed with univariate analysis. Differences in categorical data are evaluated by the X2 test. A P value below 0.05 is regarded as indicating a significant difference. Results: The data results accord with the widely held view that complete excision of intravenous leiomyomata achieves favorable prognoses regarding remission. The efficacy of using Gonadotropin releasing hormone agonists to prevent growth or recurrence of tumors in unresected or incompletely resected intravenous leiomyomatosis foci. Conclusion: If complete surgical resection is not possible, partial resection followed by hormone therapy using gonadotropin-releasing hormone agonists is recommended, which in this study achieved the same favorable prognosis with regard to remission.http://www.sciencedirect.com/science/article/pii/S1028455917300876LeiomyomaIntravenous/intravascular leiomyomatosisHysterectomyGnRH-A |
| spellingShingle | Hui-Ying Low Yu Zhao Kuo-Shu Huang Huang-Pin Shen Pei-Ju Wu Chih-Jen Tseng Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review Taiwanese Journal of Obstetrics & Gynecology Leiomyoma Intravenous/intravascular leiomyomatosis Hysterectomy GnRH-A |
| title | Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review |
| title_full | Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review |
| title_fullStr | Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review |
| title_full_unstemmed | Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review |
| title_short | Intravenous leiomyomatosis of the uterus: A clinicopathological analysis of nine cases and literature review |
| title_sort | intravenous leiomyomatosis of the uterus a clinicopathological analysis of nine cases and literature review |
| topic | Leiomyoma Intravenous/intravascular leiomyomatosis Hysterectomy GnRH-A |
| url | http://www.sciencedirect.com/science/article/pii/S1028455917300876 |
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