Eternal sunshine of the spotless cycle
Abstract Understanding the quantitative principles underlying the durations of each of the four cell cycle phases has remained a challenge, despite the extensive knowledge on the molecular components and mechanisms related to cell cycle control. In their recent study, Purvis and colleagues (Chao et ...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Springer Nature
2019-04-01
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| Series: | Molecular Systems Biology |
| Online Access: | https://doi.org/10.15252/msb.20198864 |
| _version_ | 1827014837974073344 |
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| author | Lendert Gelens Silvia DM Santos |
| author_facet | Lendert Gelens Silvia DM Santos |
| author_sort | Lendert Gelens |
| collection | DOAJ |
| description | Abstract Understanding the quantitative principles underlying the durations of each of the four cell cycle phases has remained a challenge, despite the extensive knowledge on the molecular components and mechanisms related to cell cycle control. In their recent study, Purvis and colleagues (Chao et al, 2019) quantify cell cycle phase durations in human cells and propose a model whereby cell cycle progression in single cells is a succession of uncoupled, memoryless phases, each composed of a characteristic rate and number of steps. |
| first_indexed | 2024-03-07T17:43:58Z |
| format | Article |
| id | doaj.art-795c0ce54f414a2da7410380d5f2b7bd |
| institution | Directory Open Access Journal |
| issn | 1744-4292 |
| language | English |
| last_indexed | 2025-02-18T14:15:15Z |
| publishDate | 2019-04-01 |
| publisher | Springer Nature |
| record_format | Article |
| series | Molecular Systems Biology |
| spelling | doaj.art-795c0ce54f414a2da7410380d5f2b7bd2024-10-28T09:18:01ZengSpringer NatureMolecular Systems Biology1744-42922019-04-011541210.15252/msb.20198864Eternal sunshine of the spotless cycleLendert Gelens0Silvia DM Santos1Laboratory of Dynamics in Biological Systems, Department of Cellular and Molecular Medicine, University of LeuvenQuantitative Cell Biology Laboratory, The Francis Crick InstituteAbstract Understanding the quantitative principles underlying the durations of each of the four cell cycle phases has remained a challenge, despite the extensive knowledge on the molecular components and mechanisms related to cell cycle control. In their recent study, Purvis and colleagues (Chao et al, 2019) quantify cell cycle phase durations in human cells and propose a model whereby cell cycle progression in single cells is a succession of uncoupled, memoryless phases, each composed of a characteristic rate and number of steps.https://doi.org/10.15252/msb.20198864 |
| spellingShingle | Lendert Gelens Silvia DM Santos Eternal sunshine of the spotless cycle Molecular Systems Biology |
| title | Eternal sunshine of the spotless cycle |
| title_full | Eternal sunshine of the spotless cycle |
| title_fullStr | Eternal sunshine of the spotless cycle |
| title_full_unstemmed | Eternal sunshine of the spotless cycle |
| title_short | Eternal sunshine of the spotless cycle |
| title_sort | eternal sunshine of the spotless cycle |
| url | https://doi.org/10.15252/msb.20198864 |
| work_keys_str_mv | AT lendertgelens eternalsunshineofthespotlesscycle AT silviadmsantos eternalsunshineofthespotlesscycle |