Identification of Co-Existing Mutations and Gene Expression Trends Associated With K13-Mediated Artemisinin Resistance in Plasmodium falciparum

Identification of Co-Existing Mutations and Gene Expression Trends Associated With K13-Mediated Artemisinin Resistance in Plasmodium falciparum

Plasmodium falciparum infects millions and kills thousands of people annually the world over. With the emergence of artemisinin and/or multidrug resistant strains of the pathogen, it has become even more challenging to control and eliminate the disease. Multiomics studies of the parasite have starte...

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Bibliographic Details
Main Authors: Mukul Rawat, Abhishek Kanyal, Deepak Choubey, Bhagyashree Deshmukh, Rashim Malhotra, DV Mamatharani, Anjani Gopal Rao, Krishanpal Karmodiya
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Genetics
Subjects:
malaria
Plasmodium falciparum
artemisinin resistance
Kelch13 mutations
genomics
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.824483/full

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