Podoplanin promotes cancer-associated thrombosis and contributes to the unfavorable overall survival in an ectopic xenograft mouse model of oral cancer

Background: Podoplanin (PDPN) is a transmembrane glycoprotein that mediates tumor cell-induced platelets aggregation in different cancer types. Emerging data indicate that PDPN is a marker for poor prognosis of human oral squamous cell carcinoma (OSCC). However, the functional impacts of PDPN on can...

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Bibliographic Details
Main Authors: Hsing-Ying Lee, Ni-Yen Yu, Shiang-Hsuan Lee, Hui-Ju Tsai, Chih-Ching Wu, Ju-Chien Cheng, Ding-Ping Chen, Ying-Ru Wang, Ching-Ping Tseng
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:Biomedical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S231941701930469X