| Summary: | Atherosclerosis is a chronic inflammatory disease occurring in arterial wall over many decades,
often leading to acute cardiovascular event. The different mechanisms are involved in the
development of this disease. Oxidative stress process is recognized as an important factor for
initiation and progression of atherosclerosis. Many therapeutic approaches exist for controlling,
preventing, and treating the disease. Antioxidants are the main compounds that inhibit oxidative
stress by oxidation of radical free and including protective effect against cardiovascular disease
like atherosclerosis. Recently, several drugs about novel perspectives have been discovered which
can improve lipid profiles. This review outlines the anti-atherosclerotic property of antioxidants
in prevention and improvement atherosclerosis and its new hopes.
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