Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases
The Sustainable Development goals for 2020 included reducing all causes associated with infant and perinatal mortality in their priorities. The use of compounds with bioactive properties has been proposed as a therapeutic strategy due to their stimulating effect on the host’s immune system. Addition...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-09-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/8/10/1510 |
| _version_ | 1797552153203572736 |
|---|---|
| author | Anastasia Mantziari Seppo Salminen Hania Szajewska Jeadran Nevardo Malagón-Rojas |
| author_facet | Anastasia Mantziari Seppo Salminen Hania Szajewska Jeadran Nevardo Malagón-Rojas |
| author_sort | Anastasia Mantziari |
| collection | DOAJ |
| description | The Sustainable Development goals for 2020 included reducing all causes associated with infant and perinatal mortality in their priorities. The use of compounds with bioactive properties has been proposed as a therapeutic strategy due to their stimulating effect on the host’s immune system. Additionally, biotherapeutic products such as postbiotics, tentatively defined as compounds produced during a fermentation process that support health and well-being, promote intestinal barrier integrity without posing considerable risks to children’s health. Although this is a concept in development, there are increasing studies in the field of nutrition, chemistry, and health that aim to understand how postbiotics can help prevent different types of infections in priority populations such as minors under the age of five. The present review aims to describe the main mechanisms of action of postbiotics. In addition, it presents the available current evidence regarding the effects of postbiotics against pathogens commonly involved in pediatric infections. Postbiotics may constitute a safe alternative capable of modulating the cellular response and stimulating the host’s humoral response. |
| first_indexed | 2024-03-10T15:55:57Z |
| format | Article |
| id | doaj.art-79673285b2cc40e888b9d446afdbd4d4 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T15:55:57Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-79673285b2cc40e888b9d446afdbd4d42023-11-20T15:41:31ZengMDPI AGMicroorganisms2076-26072020-09-01810151010.3390/microorganisms8101510Postbiotics against Pathogens Commonly Involved in Pediatric Infectious DiseasesAnastasia Mantziari0Seppo Salminen1Hania Szajewska2Jeadran Nevardo Malagón-Rojas3Functional Foods Forum, Faculty of Medicine, University of Turku, 20520 Turku, FinlandFunctional Foods Forum, Faculty of Medicine, University of Turku, 20520 Turku, FinlandDepartment of Paediatrics at the Medical University of Warsaw, 02091 Warsaw, PolandFacultad de Medicina, Universidad El Bosque, 110121 Bogotá, ColombiaThe Sustainable Development goals for 2020 included reducing all causes associated with infant and perinatal mortality in their priorities. The use of compounds with bioactive properties has been proposed as a therapeutic strategy due to their stimulating effect on the host’s immune system. Additionally, biotherapeutic products such as postbiotics, tentatively defined as compounds produced during a fermentation process that support health and well-being, promote intestinal barrier integrity without posing considerable risks to children’s health. Although this is a concept in development, there are increasing studies in the field of nutrition, chemistry, and health that aim to understand how postbiotics can help prevent different types of infections in priority populations such as minors under the age of five. The present review aims to describe the main mechanisms of action of postbiotics. In addition, it presents the available current evidence regarding the effects of postbiotics against pathogens commonly involved in pediatric infections. Postbiotics may constitute a safe alternative capable of modulating the cellular response and stimulating the host’s humoral response.https://www.mdpi.com/2076-2607/8/10/1510postbioticsprobioticscommon infectious diseaseschildrenpublic health |
| spellingShingle | Anastasia Mantziari Seppo Salminen Hania Szajewska Jeadran Nevardo Malagón-Rojas Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases Microorganisms postbiotics probiotics common infectious diseases children public health |
| title | Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases |
| title_full | Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases |
| title_fullStr | Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases |
| title_full_unstemmed | Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases |
| title_short | Postbiotics against Pathogens Commonly Involved in Pediatric Infectious Diseases |
| title_sort | postbiotics against pathogens commonly involved in pediatric infectious diseases |
| topic | postbiotics probiotics common infectious diseases children public health |
| url | https://www.mdpi.com/2076-2607/8/10/1510 |
| work_keys_str_mv | AT anastasiamantziari postbioticsagainstpathogenscommonlyinvolvedinpediatricinfectiousdiseases AT sepposalminen postbioticsagainstpathogenscommonlyinvolvedinpediatricinfectiousdiseases AT haniaszajewska postbioticsagainstpathogenscommonlyinvolvedinpediatricinfectiousdiseases AT jeadrannevardomalagonrojas postbioticsagainstpathogenscommonlyinvolvedinpediatricinfectiousdiseases |