Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis

Cardiac masses are space occupying lesions within the cardiac cavities or adjacent to the pericardium. They include frequently diagnosed clinical entities such as clots and vegetations, common benign tumors such as myxomas and papillary fibroelastomas and uncommon benign or malignant primary or meta...

Full description

Bibliographic Details
Main Authors: Constantina Aggeli, Yannis Dimitroglou, Leonidas Raftopoulos, Georgia Sarri, Sophie Mavrogeni, Joyce Wong, Eleftherios Tsiamis, Costas Tsioufis
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/10/12/1088
_version_ 1797544678406488064
author Constantina Aggeli
Yannis Dimitroglou
Leonidas Raftopoulos
Georgia Sarri
Sophie Mavrogeni
Joyce Wong
Eleftherios Tsiamis
Costas Tsioufis
author_facet Constantina Aggeli
Yannis Dimitroglou
Leonidas Raftopoulos
Georgia Sarri
Sophie Mavrogeni
Joyce Wong
Eleftherios Tsiamis
Costas Tsioufis
author_sort Constantina Aggeli
collection DOAJ
description Cardiac masses are space occupying lesions within the cardiac cavities or adjacent to the pericardium. They include frequently diagnosed clinical entities such as clots and vegetations, common benign tumors such as myxomas and papillary fibroelastomas and uncommon benign or malignant primary or metastatic tumors. Given their diversity, there are no guidelines or consensus statements regarding the best diagnostic or therapeutic approach. In the past, diagnosis used to be made by the histological specimens after surgery or during the post-mortem examination. Nevertheless, evolution and increased availability of cardiovascular imaging modalities has enabled better characterization of the masses and the surrounding tissue. Transthoracic echocardiography using contrast agents can evaluate the location, the morphology and the perfusion of the mass as well as its hemodynamic effect. Transesophageal echocardiography has increased spatial and temporal resolution; hence it is superior in depicting small highly mobile masses. Cardiac magnetic resonance and cardiac computed tomography are complementary providing tissue characterization. The scope of this review is to present the role of cardiovascular imaging in the differential diagnosis of cardiac masses and to propose a step-wise diagnostic algorithm, taking into account the epidemiology and clinical presentation of the cardiac masses, as well as the availability and the incremental value of each imaging modality.
first_indexed 2024-03-10T14:04:56Z
format Article
id doaj.art-79674e4ab7d74792ae8c2a691559ccc0
institution Directory Open Access Journal
issn 2075-4418
language English
last_indexed 2024-03-10T14:04:56Z
publishDate 2020-12-01
publisher MDPI AG
record_format Article
series Diagnostics
spelling doaj.art-79674e4ab7d74792ae8c2a691559ccc02023-11-21T00:48:17ZengMDPI AGDiagnostics2075-44182020-12-011012108810.3390/diagnostics10121088Cardiac Masses: The Role of Cardiovascular Imaging in the Differential DiagnosisConstantina Aggeli0Yannis Dimitroglou1Leonidas Raftopoulos2Georgia Sarri3Sophie Mavrogeni4Joyce Wong5Eleftherios Tsiamis6Costas Tsioufis7First Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, GreeceFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, GreeceFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, GreeceFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, GreeceDepartment of Cardiology, Onassis Cardiac Surgery Centre, 17674 Kallithea, Attica, GreeceDepartment of Cardiology, Harefield Hospital and Royal Brompton Hospital, London UB96JH, UKFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, GreeceFirst Department of Cardiology, General Hospital of Athens Hippokration, University of Athens Medical School, 11527 Athens, Attica, GreeceCardiac masses are space occupying lesions within the cardiac cavities or adjacent to the pericardium. They include frequently diagnosed clinical entities such as clots and vegetations, common benign tumors such as myxomas and papillary fibroelastomas and uncommon benign or malignant primary or metastatic tumors. Given their diversity, there are no guidelines or consensus statements regarding the best diagnostic or therapeutic approach. In the past, diagnosis used to be made by the histological specimens after surgery or during the post-mortem examination. Nevertheless, evolution and increased availability of cardiovascular imaging modalities has enabled better characterization of the masses and the surrounding tissue. Transthoracic echocardiography using contrast agents can evaluate the location, the morphology and the perfusion of the mass as well as its hemodynamic effect. Transesophageal echocardiography has increased spatial and temporal resolution; hence it is superior in depicting small highly mobile masses. Cardiac magnetic resonance and cardiac computed tomography are complementary providing tissue characterization. The scope of this review is to present the role of cardiovascular imaging in the differential diagnosis of cardiac masses and to propose a step-wise diagnostic algorithm, taking into account the epidemiology and clinical presentation of the cardiac masses, as well as the availability and the incremental value of each imaging modality.https://www.mdpi.com/2075-4418/10/12/1088cardiac tumorscardiac malignanciesechocardiographytransesophageal echocardiographycontrast agentscardiac magnetic resonance
spellingShingle Constantina Aggeli
Yannis Dimitroglou
Leonidas Raftopoulos
Georgia Sarri
Sophie Mavrogeni
Joyce Wong
Eleftherios Tsiamis
Costas Tsioufis
Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis
Diagnostics
cardiac tumors
cardiac malignancies
echocardiography
transesophageal echocardiography
contrast agents
cardiac magnetic resonance
title Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis
title_full Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis
title_fullStr Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis
title_full_unstemmed Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis
title_short Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis
title_sort cardiac masses the role of cardiovascular imaging in the differential diagnosis
topic cardiac tumors
cardiac malignancies
echocardiography
transesophageal echocardiography
contrast agents
cardiac magnetic resonance
url https://www.mdpi.com/2075-4418/10/12/1088
work_keys_str_mv AT constantinaaggeli cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT yannisdimitroglou cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT leonidasraftopoulos cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT georgiasarri cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT sophiemavrogeni cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT joycewong cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT eleftheriostsiamis cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis
AT costastsioufis cardiacmassestheroleofcardiovascularimaginginthedifferentialdiagnosis