A computational investigation of the ventilation structure and maximum rate of metabolism for a physiologically based pharmacokinetic (PBPK) model of inhaled xylene

Physiologically based pharmacokinetic (PBPK) models are systems of ordinary differential equations that estimate internal doses following exposure to toxicants. Most PBPK models use standard equations to describe inhalation and concentrations in blood. This study extends previous work investigating...

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Những tác giả chính: Karen A Yokley, Jaclyn Ashcraft, Nicholas S Luke
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Bulgarian Academy of Sciences, Institute of Mathematics and Informatics 2019-02-01
Loạt:Biomath
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Truy cập trực tuyến:http://www.biomathforum.org/biomath/index.php/biomath/article/view/1270