Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors

Porous materials are currently the basis of many optical sensors because of their ability to provide a higher interaction between the light and the analyte, directly within the optical structure. In this study, mesoporous TiO<sub>2</sub> layers were fabricated using a bottom-up synthesis...

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Main Authors: David Ortiz de Zárate, Sara Serna, Salvador Ponce-Alcántara, Jaime García-Rupérez
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/14/5398
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author David Ortiz de Zárate
Sara Serna
Salvador Ponce-Alcántara
Jaime García-Rupérez
author_facet David Ortiz de Zárate
Sara Serna
Salvador Ponce-Alcántara
Jaime García-Rupérez
author_sort David Ortiz de Zárate
collection DOAJ
description Porous materials are currently the basis of many optical sensors because of their ability to provide a higher interaction between the light and the analyte, directly within the optical structure. In this study, mesoporous TiO<sub>2</sub> layers were fabricated using a bottom-up synthesis approach in order to develop optical sensing structures. In comparison with more typical top-down fabrication strategies where the bulk constitutive material is etched in order to obtain the required porous medium, the use of a bottom-up fabrication approach potentially allows increasing the interconnectivity of the pore network, hence improving the surface and depth homogeneity of the fabricated layer and reducing production costs by synthesizing the layers on a larger scale. The sensing performance of the fabricated mesoporous TiO<sub>2</sub> layers was assessed by means of the measurement of several glucose dilutions in water, estimating a limit of detection even below 0.15 mg/mL (15 mg/dL). All of these advantages make this platform a very promising candidate for the development of low-cost and high-performance optical sensors.
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spelling doaj.art-7967ecf497a444bbb5d838d3fcb9a4842023-12-03T12:13:36ZengMDPI AGSensors1424-82202022-07-012214539810.3390/s22145398Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical SensorsDavid Ortiz de Zárate0Sara Serna1Salvador Ponce-Alcántara2Jaime García-Rupérez3Nanophotonics Technology Center, Universitat Politècnica de València, Camí de Vera s/n, 46022 Valencia, SpainNanophotonics Technology Center, Universitat Politècnica de València, Camí de Vera s/n, 46022 Valencia, SpainNanophotonics Technology Center, Universitat Politècnica de València, Camí de Vera s/n, 46022 Valencia, SpainNanophotonics Technology Center, Universitat Politècnica de València, Camí de Vera s/n, 46022 Valencia, SpainPorous materials are currently the basis of many optical sensors because of their ability to provide a higher interaction between the light and the analyte, directly within the optical structure. In this study, mesoporous TiO<sub>2</sub> layers were fabricated using a bottom-up synthesis approach in order to develop optical sensing structures. In comparison with more typical top-down fabrication strategies where the bulk constitutive material is etched in order to obtain the required porous medium, the use of a bottom-up fabrication approach potentially allows increasing the interconnectivity of the pore network, hence improving the surface and depth homogeneity of the fabricated layer and reducing production costs by synthesizing the layers on a larger scale. The sensing performance of the fabricated mesoporous TiO<sub>2</sub> layers was assessed by means of the measurement of several glucose dilutions in water, estimating a limit of detection even below 0.15 mg/mL (15 mg/dL). All of these advantages make this platform a very promising candidate for the development of low-cost and high-performance optical sensors.https://www.mdpi.com/1424-8220/22/14/5398optical sensormesoporous layerbottom-up fabricationglucose sensingsol-gelTiO<sub>2</sub>
spellingShingle David Ortiz de Zárate
Sara Serna
Salvador Ponce-Alcántara
Jaime García-Rupérez
Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors
Sensors
optical sensor
mesoporous layer
bottom-up fabrication
glucose sensing
sol-gel
TiO<sub>2</sub>
title Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors
title_full Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors
title_fullStr Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors
title_full_unstemmed Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors
title_short Evaluation of Mesoporous TiO<sub>2</sub> Layers as Glucose Optical Sensors
title_sort evaluation of mesoporous tio sub 2 sub layers as glucose optical sensors
topic optical sensor
mesoporous layer
bottom-up fabrication
glucose sensing
sol-gel
TiO<sub>2</sub>
url https://www.mdpi.com/1424-8220/22/14/5398
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