Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro
The aim of this study was to investigate acid hydrolysis-bound phenols from Rosa roxburghii Tratt and their biological activities in vitro. The optimal extraction parameters were as follows: HCl concentration of 7 mol/L, extraction time of 10 h and material-liquid ratio of 1:40 g/mL. The highest yie...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2024-12-01
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| Series: | CyTA - Journal of Food |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19476337.2023.2294994 |
| _version_ | 1826928398621999104 |
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| author | Yumeng Qin Xiaoli Zhou Zhicheng Qin Yanli Wang Yaping Wang |
| author_facet | Yumeng Qin Xiaoli Zhou Zhicheng Qin Yanli Wang Yaping Wang |
| author_sort | Yumeng Qin |
| collection | DOAJ |
| description | The aim of this study was to investigate acid hydrolysis-bound phenols from Rosa roxburghii Tratt and their biological activities in vitro. The optimal extraction parameters were as follows: HCl concentration of 7 mol/L, extraction time of 10 h and material-liquid ratio of 1:40 g/mL. The highest yield of bound polyphenols was 495.64 ± 11.66 mg GAE/100 g DW. There were 24 phenolic compounds and 14 flavonoids released by acid hydrolysis. The antioxidant study showed that the RRT-BPs had a certain scavenging ability of free radicals in a dose-dependent manner. RRT-BPs showed good inhibitory activity against α-glucosidase and pancreatic lipase, respectively, and RRT-PBs acted as anticompetitive and mixed inhibitors against α-glucosidase and pancreatic lipase, respectively. Our study suggests that acid-hydrolysed bound phenols have good prebiotic properties and can be used as a supplement to existing alkaline-hydrolysed bound phenols to prevent chronic diseases such as diabetes and obesity. |
| first_indexed | 2024-03-08T13:36:23Z |
| format | Article |
| id | doaj.art-7968442a81734b859d38f50bb769453b |
| institution | Directory Open Access Journal |
| issn | 1947-6337 1947-6345 |
| language | English |
| last_indexed | 2025-02-17T15:48:45Z |
| publishDate | 2024-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | CyTA - Journal of Food |
| spelling | doaj.art-7968442a81734b859d38f50bb769453b2024-12-18T13:34:52ZengTaylor & Francis GroupCyTA - Journal of Food1947-63371947-63452024-12-0122110.1080/19476337.2023.2294994Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitroYumeng Qin0Xiaoli Zhou1Zhicheng Qin2Yanli Wang3Yaping Wang4College of Food Science and Engineering, Guiyang University, Guiyang, ChinaCollege of Food Science and Engineering, Guiyang University, Guiyang, ChinaCollege of Food Science and Engineering, Guiyang University, Guiyang, ChinaCollege of Food Science and Engineering, Guiyang University, Guiyang, ChinaCollege of Food Science and Engineering, Guiyang University, Guiyang, ChinaThe aim of this study was to investigate acid hydrolysis-bound phenols from Rosa roxburghii Tratt and their biological activities in vitro. The optimal extraction parameters were as follows: HCl concentration of 7 mol/L, extraction time of 10 h and material-liquid ratio of 1:40 g/mL. The highest yield of bound polyphenols was 495.64 ± 11.66 mg GAE/100 g DW. There were 24 phenolic compounds and 14 flavonoids released by acid hydrolysis. The antioxidant study showed that the RRT-BPs had a certain scavenging ability of free radicals in a dose-dependent manner. RRT-BPs showed good inhibitory activity against α-glucosidase and pancreatic lipase, respectively, and RRT-PBs acted as anticompetitive and mixed inhibitors against α-glucosidase and pancreatic lipase, respectively. Our study suggests that acid-hydrolysed bound phenols have good prebiotic properties and can be used as a supplement to existing alkaline-hydrolysed bound phenols to prevent chronic diseases such as diabetes and obesity.https://www.tandfonline.com/doi/10.1080/19476337.2023.2294994Rosa roxburghii Trattacid hydrolysisbound phenolicsantioxidant activitiesα-glucosidasepancreatic lipase |
| spellingShingle | Yumeng Qin Xiaoli Zhou Zhicheng Qin Yanli Wang Yaping Wang Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro CyTA - Journal of Food Rosa roxburghii Tratt acid hydrolysis bound phenolics antioxidant activities α-glucosidase pancreatic lipase |
| title | Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro |
| title_full | Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro |
| title_fullStr | Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro |
| title_full_unstemmed | Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro |
| title_short | Optimization of the acid hydrolysis process for the extraction of Rosa roxburghii Tratt-bound phenols and antioxidant, α-glucosidase and lipase inhibitory activities in vitro |
| title_sort | optimization of the acid hydrolysis process for the extraction of rosa roxburghii tratt bound phenols and antioxidant α glucosidase and lipase inhibitory activities in vitro |
| topic | Rosa roxburghii Tratt acid hydrolysis bound phenolics antioxidant activities α-glucosidase pancreatic lipase |
| url | https://www.tandfonline.com/doi/10.1080/19476337.2023.2294994 |
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