Comparative Effect of MSC Secretome to MSC Co-culture on Cardiomyocyte Gene Expression Under Hypoxic Conditions in vitro

Comparative Effect of MSC Secretome to MSC Co-culture on Cardiomyocyte Gene Expression Under Hypoxic Conditions in vitro

IntroductionDespite major leaps in regenerative medicine, the regeneration of cardiomyocytes after ischemic conditions remains to elucidate. It is crucial to understand hypoxia induced cellular mechanisms to provide advanced treatment options, including the use of stem cell paracrine factors for myo...

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Bibliographic Details
Main Authors: Nina Kastner, Julia Mester-Tonczar, Johannes Winkler, Denise Traxler, Andreas Spannbauer, Beate M. Rüger, Georg Goliasch, Noemi Pavo, Mariann Gyöngyösi, Katrin Zlabinger
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
human cardiomyocytes
hypoxia
regeneration
cell therapy
MSC secretome
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.502213/full

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