Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults
Abstract Background In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. Methods A total of 1625 participants without MetS were re...
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| Format: | Article |
| Language: | English |
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BMC
2021-03-01
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| Series: | Diabetology & Metabolic Syndrome |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13098-021-00648-1 |
| _version_ | 1818430449950654464 |
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| author | Hossein Farhadnejad Karim Parastouei Hosein Rostami Parvin Mirmiran Fereidoun Azizi |
| author_facet | Hossein Farhadnejad Karim Parastouei Hosein Rostami Parvin Mirmiran Fereidoun Azizi |
| author_sort | Hossein Farhadnejad |
| collection | DOAJ |
| description | Abstract Background In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. Methods A total of 1625 participants without MetS were recruited from among participants of the Tehran Lipid and Glucose Study(2006–2008) and followed a mean of 6.1 years. Dietary data of subjects were collected using a food frequency questionnaire at baseline to determine LIS and DIS. Multivariable logistic regression models, were used to calculate the odds ratio (ORs) and 95 % confidence interval (CI) of MetS across tertiles of DIS and LIS. Results Mean ± SD age of individuals (45.8 % men) was 37.5 ± 13.4 years. Median (25–75 interquartile range) DIS and LIS for all participants was 0.80 (− 2.94, 3.64) and 0.48 (− 0.18, − 0.89), respectively. During the study follow-up, 291 (17.9 %) new cases of MetS were identified. Based on the age and sex-adjusted model, a positive association was found between LIS (OR = 7.56; 95% CI 5.10–11.22, P for trend < 0.001) and risk of MetS, however, the association of DIS and risk of MetS development was not statistically significant (OR = 1.30;95% CI 0.93–1.80, P for trend = 0.127). In the multivariable model, after adjustment for confounding variables, including age, sex, body mass index, physical activity, smoking, and energy intake, the risk of MetS is increased across tertiles of DIS (OR = 1.59; 95% CI 1.09–2.33, P for trend = 0.015) and LIS(OR = 8.38; 95% CI 5.51–12.7, P for trend < 0.001). Conclusions The findings of the current study showed that greater adherence to LIS and DIS, determined to indicate the inflammatory potential of diet and lifestyle, are associated with increased the risk of MetS. |
| first_indexed | 2024-12-14T15:33:36Z |
| format | Article |
| id | doaj.art-7969228fd320456a89608d83c0b9102e |
| institution | Directory Open Access Journal |
| issn | 1758-5996 |
| language | English |
| last_indexed | 2024-12-14T15:33:36Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Diabetology & Metabolic Syndrome |
| spelling | doaj.art-7969228fd320456a89608d83c0b9102e2022-12-21T22:55:48ZengBMCDiabetology & Metabolic Syndrome1758-59962021-03-0113111010.1186/s13098-021-00648-1Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adultsHossein Farhadnejad0Karim Parastouei1Hosein Rostami2Parvin Mirmiran3Fereidoun Azizi4Health Research Center, Life Style Institute, Baqiyatallah University of Medical SciencesHealth Research Center, Life Style Institute, Baqiyatallah University of Medical SciencesHealth Research Center, Life Style Institute, Baqiyatallah University of Medical SciencesNutrition and Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical SciencesAbstract Background In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. Methods A total of 1625 participants without MetS were recruited from among participants of the Tehran Lipid and Glucose Study(2006–2008) and followed a mean of 6.1 years. Dietary data of subjects were collected using a food frequency questionnaire at baseline to determine LIS and DIS. Multivariable logistic regression models, were used to calculate the odds ratio (ORs) and 95 % confidence interval (CI) of MetS across tertiles of DIS and LIS. Results Mean ± SD age of individuals (45.8 % men) was 37.5 ± 13.4 years. Median (25–75 interquartile range) DIS and LIS for all participants was 0.80 (− 2.94, 3.64) and 0.48 (− 0.18, − 0.89), respectively. During the study follow-up, 291 (17.9 %) new cases of MetS were identified. Based on the age and sex-adjusted model, a positive association was found between LIS (OR = 7.56; 95% CI 5.10–11.22, P for trend < 0.001) and risk of MetS, however, the association of DIS and risk of MetS development was not statistically significant (OR = 1.30;95% CI 0.93–1.80, P for trend = 0.127). In the multivariable model, after adjustment for confounding variables, including age, sex, body mass index, physical activity, smoking, and energy intake, the risk of MetS is increased across tertiles of DIS (OR = 1.59; 95% CI 1.09–2.33, P for trend = 0.015) and LIS(OR = 8.38; 95% CI 5.51–12.7, P for trend < 0.001). Conclusions The findings of the current study showed that greater adherence to LIS and DIS, determined to indicate the inflammatory potential of diet and lifestyle, are associated with increased the risk of MetS.https://doi.org/10.1186/s13098-021-00648-1DietLifestyleInflammationMetabolic syndromeMetSAdult |
| spellingShingle | Hossein Farhadnejad Karim Parastouei Hosein Rostami Parvin Mirmiran Fereidoun Azizi Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults Diabetology & Metabolic Syndrome Diet Lifestyle Inflammation Metabolic syndrome MetS Adult |
| title | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
| title_full | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
| title_fullStr | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
| title_full_unstemmed | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
| title_short | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
| title_sort | dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in iranian adults |
| topic | Diet Lifestyle Inflammation Metabolic syndrome MetS Adult |
| url | https://doi.org/10.1186/s13098-021-00648-1 |
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