MyoD-Induced Trans-Differentiation: A Paradigm for Dissecting the Molecular Mechanisms of Cell Commitment, Differentiation and Reprogramming

MyoD-Induced Trans-Differentiation: A Paradigm for Dissecting the Molecular Mechanisms of Cell Commitment, Differentiation and Reprogramming

The discovery of the skeletal muscle-specific transcription factor MyoD represents a milestone in the field of transcriptional regulation during differentiation and cell-fate reprogramming. MyoD was the first tissue-specific factor found capable of converting non-muscle somatic cells into skeletal m...

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Bibliographic Details
Main Authors: Cecilia Battistelli, Sabrina Garbo, Rossella Maione
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
MyoD
myogenic conversion
forced differentiation
chromatin regulation
Online Access:https://www.mdpi.com/2073-4409/11/21/3435

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