4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione
In the title isoquinolinedione derivative, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a distorted envelope conformation. The thiazole ring is essentially planar [maximum deviation = 0.004 (1) Å] and is inclined at a dihe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2010-04-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536810010469 |
| Summary: | In the title isoquinolinedione derivative, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a distorted envelope conformation. The thiazole ring is essentially planar [maximum deviation = 0.004 (1) Å] and is inclined at a dihedral angle of 31.08 (3)° with respect to the mean plane through the tetrahydroisoquinoline ring system. In the crystal structure, intermolecular O—H...O and C—H...O interactions link adjacent molecules into a three-dimensional extended network. The crystal structure is further stabilized by weak C—H...π interactions. |
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| ISSN: | 1600-5368 |