4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione
In the title isoquinolinedione derivative, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a distorted envelope conformation. The thiazole ring is essentially planar [maximum deviation = 0.004 (1) Å] and is inclined at a dihe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2010-04-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536810010469 |
| _version_ | 1818286305078935552 |
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| author | Hoong-Kun Fun Jia Hao Goh Haitao Yu Yan Zhang |
| author_facet | Hoong-Kun Fun Jia Hao Goh Haitao Yu Yan Zhang |
| author_sort | Hoong-Kun Fun |
| collection | DOAJ |
| description | In the title isoquinolinedione derivative, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a distorted envelope conformation. The thiazole ring is essentially planar [maximum deviation = 0.004 (1) Å] and is inclined at a dihedral angle of 31.08 (3)° with respect to the mean plane through the tetrahydroisoquinoline ring system. In the crystal structure, intermolecular O—H...O and C—H...O interactions link adjacent molecules into a three-dimensional extended network. The crystal structure is further stabilized by weak C—H...π interactions. |
| first_indexed | 2024-12-13T01:22:29Z |
| format | Article |
| id | doaj.art-796be70ad2a14368be075cc582996769 |
| institution | Directory Open Access Journal |
| issn | 1600-5368 |
| language | English |
| last_indexed | 2024-12-13T01:22:29Z |
| publishDate | 2010-04-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | Acta Crystallographica Section E |
| spelling | doaj.art-796be70ad2a14368be075cc5829967692022-12-22T00:04:13ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682010-04-01664o940o94110.1107/S16005368100104694-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dioneHoong-Kun FunJia Hao GohHaitao YuYan ZhangIn the title isoquinolinedione derivative, C16H16N2O3S, the piperidine ring in the tetrahydroisoquinoline ring system adopts a distorted envelope conformation. The thiazole ring is essentially planar [maximum deviation = 0.004 (1) Å] and is inclined at a dihedral angle of 31.08 (3)° with respect to the mean plane through the tetrahydroisoquinoline ring system. In the crystal structure, intermolecular O—H...O and C—H...O interactions link adjacent molecules into a three-dimensional extended network. The crystal structure is further stabilized by weak C—H...π interactions.http://scripts.iucr.org/cgi-bin/paper?S1600536810010469 |
| spellingShingle | Hoong-Kun Fun Jia Hao Goh Haitao Yu Yan Zhang 4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione Acta Crystallographica Section E |
| title | 4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione |
| title_full | 4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione |
| title_fullStr | 4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione |
| title_full_unstemmed | 4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione |
| title_short | 4-[(2,4-Dimethylthiazol-5-yl)methyl]-4-hydroxy-2-methylisoquinoline-1,3(2H,4H)-dione |
| title_sort | 4 2 4 dimethylthiazol 5 yl methyl 4 hydroxy 2 methylisoquinoline 1 3 2h 4h dione |
| url | http://scripts.iucr.org/cgi-bin/paper?S1600536810010469 |
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