Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation

Chorea has often been associated with lesions in the basal ganglia and in the sub thalamic nucleus. It is possible for a patient with chorea-ballismus to have hyperglycemia at the initial presentation. We hereby present a case of an 81-year-old female, who was on treatment for type 2 diabetes mell...

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Main Authors: Pendela Venkata Satish, Kudaravalli Pujitha, Neha Agrawal, Thomas Mathew, Sudha Vidyasagar
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-05-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/9939/27266_CE(RA1)_F(T)_PF1(P_PG)_PFA(PG_SS).pdf
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author Pendela Venkata Satish
Kudaravalli Pujitha
Neha Agrawal
Thomas Mathew
Sudha Vidyasagar
author_facet Pendela Venkata Satish
Kudaravalli Pujitha
Neha Agrawal
Thomas Mathew
Sudha Vidyasagar
author_sort Pendela Venkata Satish
collection DOAJ
description Chorea has often been associated with lesions in the basal ganglia and in the sub thalamic nucleus. It is possible for a patient with chorea-ballismus to have hyperglycemia at the initial presentation. We hereby present a case of an 81-year-old female, who was on treatment for type 2 diabetes mellitus and presented to us with sub acute onset of abnormal movements of right side of the body. She had semi purposeful, rapid and jerky movements of right upper limb and lower limb along with abnormal tongue movements. Laboratory data showed very high blood glucose levels, urine ketones were positive and pH of arterial blood was normal. MRI brain showed hyperintensities in right basal ganglia. So, hyperglycemia induced hemichorea was considered as a possibility and she was treated with insulin. These abnormal movements decreased subsequently with treatment and patient is doing better in the follow-up visits. This presentation is extremely rare, as review of literature showed similar presentations in patients with non ketotic hyperglycemia but not reported so far in diabetic ketosis.
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spelling doaj.art-796d6676dbfe41dc92af7dd2de11fb212022-12-21T18:39:58ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-05-01115OD24OD2510.7860/JCDR/2017/27266.9939Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual PresentationPendela Venkata Satish0Kudaravalli Pujitha1Neha Agrawal2Thomas Mathew3Sudha Vidyasagar4Junior Resident, Department of Medicine, K.M.C., Manipal, Karnataka, India.House Surgeon, Department of Medicine, K.M.C., Manipal, Karnataka, India.Junior Resident, Department of Medicine, K.M.C., Manipal, Karnataka, India.Junior Resident, Department of Medicine, K.M.C., Manipal, Karnataka, India.Professor and Head, Department of Medicine, K.M.C., Manipal, Karnataka, India.Chorea has often been associated with lesions in the basal ganglia and in the sub thalamic nucleus. It is possible for a patient with chorea-ballismus to have hyperglycemia at the initial presentation. We hereby present a case of an 81-year-old female, who was on treatment for type 2 diabetes mellitus and presented to us with sub acute onset of abnormal movements of right side of the body. She had semi purposeful, rapid and jerky movements of right upper limb and lower limb along with abnormal tongue movements. Laboratory data showed very high blood glucose levels, urine ketones were positive and pH of arterial blood was normal. MRI brain showed hyperintensities in right basal ganglia. So, hyperglycemia induced hemichorea was considered as a possibility and she was treated with insulin. These abnormal movements decreased subsequently with treatment and patient is doing better in the follow-up visits. This presentation is extremely rare, as review of literature showed similar presentations in patients with non ketotic hyperglycemia but not reported so far in diabetic ketosis.https://jcdr.net/articles/PDF/9939/27266_CE(RA1)_F(T)_PF1(P_PG)_PFA(PG_SS).pdfchoreo-athetoid movementsdiabetic ketosistype 2 diabetes mellitus
spellingShingle Pendela Venkata Satish
Kudaravalli Pujitha
Neha Agrawal
Thomas Mathew
Sudha Vidyasagar
Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation
Journal of Clinical and Diagnostic Research
choreo-athetoid movements
diabetic ketosis
type 2 diabetes mellitus
title Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation
title_full Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation
title_fullStr Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation
title_full_unstemmed Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation
title_short Hemi-Chorea in a Patient with Ketotic Hyperglycemia: An Unusual Presentation
title_sort hemi chorea in a patient with ketotic hyperglycemia an unusual presentation
topic choreo-athetoid movements
diabetic ketosis
type 2 diabetes mellitus
url https://jcdr.net/articles/PDF/9939/27266_CE(RA1)_F(T)_PF1(P_PG)_PFA(PG_SS).pdf
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AT nehaagrawal hemichoreainapatientwithketotichyperglycemiaanunusualpresentation
AT thomasmathew hemichoreainapatientwithketotichyperglycemiaanunusualpresentation
AT sudhavidyasagar hemichoreainapatientwithketotichyperglycemiaanunusualpresentation