JCPyV VP1 Mutations in Progressive Multifocal Leukoencephalopathy: Altering Tropism or Mediating Immune Evasion?

Polyomaviruses are ubiquitous human pathogens that cause lifelong, asymptomatic infections in healthy individuals. Although these viruses are restrained by an intact immune system, immunocompromised individuals are at risk for developing severe diseases driven by resurgent viral replication. In part...

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Bibliographic Details
Main Authors: Matthew D. Lauver, Aron E. Lukacher
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/10/1156