Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy
Formulas adapted to infant feeding, although most of the time made from cow’s milk proteins, can be made from hydrolyzed rice protein but they must be classified as “formulas for specific medical needs”, according to European regulations. The nutritional quality of rice proteins is thus suitable to...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-08-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/12/9/2654 |
| _version_ | 1797555055286550528 |
|---|---|
| author | Christophe Dupont Alain Bocquet Daniel Tomé Marie Bernard Florence Campeotto Pascale Dumond Anna Essex Marie-Laure Frelut Lydie Guénard-Bilbault Gideon Lack Agnès Linglart François Payot Alain Taieb Nicolas Kalach |
| author_facet | Christophe Dupont Alain Bocquet Daniel Tomé Marie Bernard Florence Campeotto Pascale Dumond Anna Essex Marie-Laure Frelut Lydie Guénard-Bilbault Gideon Lack Agnès Linglart François Payot Alain Taieb Nicolas Kalach |
| author_sort | Christophe Dupont |
| collection | DOAJ |
| description | Formulas adapted to infant feeding, although most of the time made from cow’s milk proteins, can be made from hydrolyzed rice protein but they must be classified as “formulas for specific medical needs”, according to European regulations. The nutritional quality of rice proteins is thus suitable to be used in infant formulas giving that it is supplemented by certain amino acids which can be lacking. Besides, hydrolysis is required to facilitate their water solubility and digestibility. Owing to a low allergenicity of rice and to the absence of the cross-allergy between milk proteins and rice proteins, these formulas are adapted to the diet of children with cow’s milk protein allergy (CMPA), which explains their growing use in some countries. However, CMPA, an expanding disorder, has consequences for growth, bone mineralization, and often has an association with allergy to other foods, including cow’s milk extensive hydrolysate, so that a surveillance of the adaption of hydrolyzed rice protein formulas (HRPF) to CMPA, the absence of unexpected side effects, and the appropriate response to its various health hazards seems mandatory. This paper analyses the health problem deriving from CMPA, the industrial development of hydrolyzed rice protein formulas, and the limited number of clinical studies, which confirms, at the moment, a good allergic tolerance and safety. The goal is to better advise heath care professionals on their use of HRPFs during CMPA. |
| first_indexed | 2024-03-10T16:40:51Z |
| format | Article |
| id | doaj.art-7976e6794006477bbd44b975f9c9ef9b |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T16:40:51Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-7976e6794006477bbd44b975f9c9ef9b2023-11-20T11:59:38ZengMDPI AGNutrients2072-66432020-08-01129265410.3390/nu12092654Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk AllergyChristophe Dupont0Alain Bocquet1Daniel Tomé2Marie Bernard3Florence Campeotto4Pascale Dumond5Anna Essex6Marie-Laure Frelut7Lydie Guénard-Bilbault8Gideon Lack9Agnès Linglart10François Payot11Alain Taieb12Nicolas Kalach13Pediatric Gastroenterology Department, Paris-Descartes University, 75006 Paris, FranceAssociation Française de Pédiatrie Ambulatoire (French Association of Ambulatory Paediatrics), 33400 Talence, FranceUMR Nutrition Physiology and Ingestive Behavior, AgroParisTech, INRA, Paris-Saclay University, 75005 Paris, FranceCharles Nicolle Hospital, 76031 Rouen, FrancePediatric Gastroenterology Department, APHP Necker-Enfants Malades Hospital, 750015 Paris, FrancePediatric Allergy Department, Children’s Hospital, University Hospital of Nancy, 54000 Vandoeuvre les Nancy, FranceSodilac Employee, Sodilac, 92000 Levallois, FranceAssociation Française de Pédiatrie Ambulatoire (French Association of Ambulatory Paediatrics), 33400 Talence, FranceMedical General and Allergy Practice, 67400 Illkirch Graffenstaden, FrancePaediatric Allergy Research Group, Department of Women and Children’s Health, School of Life Course Sciences, King’s College London, London WC2R ELS, UKINSERM-U1185, Paris Sud Paris-Saclay University, 75005 Paris, FrancePediatric Practice, 69006 Lyon, FranceDepartment of Dermatology and Pediatric Dermatology, Bordeaux University Hospital, 33000 Bordeaux, FranceDepartment of Paediatrics, Saint Antoine Paediatric Hospital, Saint Vincent de Paul Hospital, Groupement des Hôpitaux de l’Institut Catholique de Lille (GHICL), Catholic University of Lille, 59000 Lille, FranceFormulas adapted to infant feeding, although most of the time made from cow’s milk proteins, can be made from hydrolyzed rice protein but they must be classified as “formulas for specific medical needs”, according to European regulations. The nutritional quality of rice proteins is thus suitable to be used in infant formulas giving that it is supplemented by certain amino acids which can be lacking. Besides, hydrolysis is required to facilitate their water solubility and digestibility. Owing to a low allergenicity of rice and to the absence of the cross-allergy between milk proteins and rice proteins, these formulas are adapted to the diet of children with cow’s milk protein allergy (CMPA), which explains their growing use in some countries. However, CMPA, an expanding disorder, has consequences for growth, bone mineralization, and often has an association with allergy to other foods, including cow’s milk extensive hydrolysate, so that a surveillance of the adaption of hydrolyzed rice protein formulas (HRPF) to CMPA, the absence of unexpected side effects, and the appropriate response to its various health hazards seems mandatory. This paper analyses the health problem deriving from CMPA, the industrial development of hydrolyzed rice protein formulas, and the limited number of clinical studies, which confirms, at the moment, a good allergic tolerance and safety. The goal is to better advise heath care professionals on their use of HRPFs during CMPA.https://www.mdpi.com/2072-6643/12/9/2654childrenricehydrolyzed proteincow’s milk allergy |
| spellingShingle | Christophe Dupont Alain Bocquet Daniel Tomé Marie Bernard Florence Campeotto Pascale Dumond Anna Essex Marie-Laure Frelut Lydie Guénard-Bilbault Gideon Lack Agnès Linglart François Payot Alain Taieb Nicolas Kalach Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy Nutrients children rice hydrolyzed protein cow’s milk allergy |
| title | Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy |
| title_full | Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy |
| title_fullStr | Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy |
| title_full_unstemmed | Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy |
| title_short | Hydrolyzed Rice Protein-Based Formulas, a Vegetal Alternative in Cow’s Milk Allergy |
| title_sort | hydrolyzed rice protein based formulas a vegetal alternative in cow s milk allergy |
| topic | children rice hydrolyzed protein cow’s milk allergy |
| url | https://www.mdpi.com/2072-6643/12/9/2654 |
| work_keys_str_mv | AT christophedupont hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT alainbocquet hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT danieltome hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT mariebernard hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT florencecampeotto hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT pascaledumond hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT annaessex hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT marielaurefrelut hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT lydieguenardbilbault hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT gideonlack hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT agneslinglart hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT francoispayot hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT alaintaieb hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy AT nicolaskalach hydrolyzedriceproteinbasedformulasavegetalalternativeincowsmilkallergy |