Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens

Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens

Abstract Background Plasmodium falciparum infections are especially severe in pregnant women because infected erythrocytes (IE) express VAR2CSA, a ligand that binds to placental trophoblasts, causing IE to accumulate in the placenta. Resulting inflammation and pathology increases a woman’s risk of a...

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Bibliographic Details
Main Authors: Chathura Siriwardhana, Rui Fang, Ali Salanti, Rose G. F. Leke, Naveen Bobbili, Diane Wallace Taylor, John J. Chen
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Malaria Journal
Subjects:
Predictive models
Placental malaria
Multiplex assays
VAR2CSA
Online Access:http://link.springer.com/article/10.1186/s12936-017-2041-3

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