Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula
BackgroundSclerosing epithelioid fibrosarcoma (SEF) is an extremely rare, aggressive malignant subtype of fibrosarcoma. Only dozens of cases of primary SEF in the bone have been reported so far, without case involving fibula reported in literature to date. Herein we report the first case of primary...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-11-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2020.603127/full |
| _version_ | 1819226742032695296 |
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| author | Qiaoling Ding Xiaotong Shao Xiaocao Liu Yanbiao Fu Fengbo Huang Chao Wang |
| author_facet | Qiaoling Ding Xiaotong Shao Xiaocao Liu Yanbiao Fu Fengbo Huang Chao Wang |
| author_sort | Qiaoling Ding |
| collection | DOAJ |
| description | BackgroundSclerosing epithelioid fibrosarcoma (SEF) is an extremely rare, aggressive malignant subtype of fibrosarcoma. Only dozens of cases of primary SEF in the bone have been reported so far, without case involving fibula reported in literature to date. Herein we report the first case of primary SEF in the right fibula in a 19-year-old man. In this case report, we firstly give a comprehensive description of fibula SEF, including its complete clinical course and radiological findings.Case PresentationA 19-year-old man presented with a half-year history of soreness in the right lower leg. Contrast-enhanced computed tomography (CE-CT) and magnetic resonance imaging (MRI) of the right lower leg were performed. Based on the radiological examinations, a diagnosis of malignant tumor arising in the fibular diaphysis was made. Final diagnosis of primary SEF in the right fibula was confirmed by histopathological and immunohistochemical examinations after surgical resection. The patient had no signs of recurrence or metastasis during a 24-month follow-up.ConclusionWe report an exceedingly rare case of primary SEF in the right fibula and its radiological features with CE-CT and MRI. |
| first_indexed | 2024-12-23T10:30:19Z |
| format | Article |
| id | doaj.art-79891ba88f284e5cb36fda4c113024aa |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-12-23T10:30:19Z |
| publishDate | 2020-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-79891ba88f284e5cb36fda4c113024aa2022-12-21T17:50:27ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2020-11-011010.3389/fonc.2020.603127603127Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right FibulaQiaoling Ding0Xiaotong Shao1Xiaocao Liu2Yanbiao Fu3Fengbo Huang4Chao Wang5Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Pathology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaDepartment of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaBackgroundSclerosing epithelioid fibrosarcoma (SEF) is an extremely rare, aggressive malignant subtype of fibrosarcoma. Only dozens of cases of primary SEF in the bone have been reported so far, without case involving fibula reported in literature to date. Herein we report the first case of primary SEF in the right fibula in a 19-year-old man. In this case report, we firstly give a comprehensive description of fibula SEF, including its complete clinical course and radiological findings.Case PresentationA 19-year-old man presented with a half-year history of soreness in the right lower leg. Contrast-enhanced computed tomography (CE-CT) and magnetic resonance imaging (MRI) of the right lower leg were performed. Based on the radiological examinations, a diagnosis of malignant tumor arising in the fibular diaphysis was made. Final diagnosis of primary SEF in the right fibula was confirmed by histopathological and immunohistochemical examinations after surgical resection. The patient had no signs of recurrence or metastasis during a 24-month follow-up.ConclusionWe report an exceedingly rare case of primary SEF in the right fibula and its radiological features with CE-CT and MRI.https://www.frontiersin.org/articles/10.3389/fonc.2020.603127/fullbone tumorfibulasclerosing epithelioid fibrosarcomacontrast-enhanced computed tomographymagnetic resonance imaging |
| spellingShingle | Qiaoling Ding Xiaotong Shao Xiaocao Liu Yanbiao Fu Fengbo Huang Chao Wang Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula Frontiers in Oncology bone tumor fibula sclerosing epithelioid fibrosarcoma contrast-enhanced computed tomography magnetic resonance imaging |
| title | Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula |
| title_full | Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula |
| title_fullStr | Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula |
| title_full_unstemmed | Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula |
| title_short | Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula |
| title_sort | case report radiological features of sclerosing epithelioid fibrosarcoma in the right fibula |
| topic | bone tumor fibula sclerosing epithelioid fibrosarcoma contrast-enhanced computed tomography magnetic resonance imaging |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2020.603127/full |
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