Technology for the formation of engineered microvascular network models and their biomedical applications
Abstract Tissue engineering and regenerative medicine have made great progress in recent decades, as the fields of bioengineering, materials science, and stem cell biology have converged, allowing tissue engineers to replicate the structure and function of various levels of the vascular tree. Noneth...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2024-03-01
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| Series: | Nano Convergence |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40580-024-00416-7 |
| _version_ | 1797273602771386368 |
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| author | He Li Yucheng Shang Jinfeng Zeng Michiya Matsusaki |
| author_facet | He Li Yucheng Shang Jinfeng Zeng Michiya Matsusaki |
| author_sort | He Li |
| collection | DOAJ |
| description | Abstract Tissue engineering and regenerative medicine have made great progress in recent decades, as the fields of bioengineering, materials science, and stem cell biology have converged, allowing tissue engineers to replicate the structure and function of various levels of the vascular tree. Nonetheless, the lack of a fully functional vascular system to efficiently supply oxygen and nutrients has hindered the clinical application of bioengineered tissues for transplantation. To investigate vascular biology, drug transport, disease progression, and vascularization of engineered tissues for regenerative medicine, we have analyzed different approaches for designing microvascular networks to create models. This review discusses recent advances in the field of microvascular tissue engineering, explores potential future challenges, and offers methodological recommendations. |
| first_indexed | 2024-03-07T14:46:46Z |
| format | Article |
| id | doaj.art-798f220aa08f424c95a4129452d6420a |
| institution | Directory Open Access Journal |
| issn | 2196-5404 |
| language | English |
| last_indexed | 2024-03-07T14:46:46Z |
| publishDate | 2024-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Nano Convergence |
| spelling | doaj.art-798f220aa08f424c95a4129452d6420a2024-03-05T19:56:36ZengSpringerOpenNano Convergence2196-54042024-03-0111112010.1186/s40580-024-00416-7Technology for the formation of engineered microvascular network models and their biomedical applicationsHe Li0Yucheng Shang1Jinfeng Zeng2Michiya Matsusaki3Department of Applied Chemistry, Graduate School of Engineering, Osaka UniversityDepartment of Applied Chemistry, Graduate School of Engineering, Osaka UniversityDepartment of Applied Chemistry, Graduate School of Engineering, Osaka UniversityDepartment of Applied Chemistry, Graduate School of Engineering, Osaka UniversityAbstract Tissue engineering and regenerative medicine have made great progress in recent decades, as the fields of bioengineering, materials science, and stem cell biology have converged, allowing tissue engineers to replicate the structure and function of various levels of the vascular tree. Nonetheless, the lack of a fully functional vascular system to efficiently supply oxygen and nutrients has hindered the clinical application of bioengineered tissues for transplantation. To investigate vascular biology, drug transport, disease progression, and vascularization of engineered tissues for regenerative medicine, we have analyzed different approaches for designing microvascular networks to create models. This review discusses recent advances in the field of microvascular tissue engineering, explores potential future challenges, and offers methodological recommendations.https://doi.org/10.1186/s40580-024-00416-7Microvascular networkTissue engineeringBiomaterials |
| spellingShingle | He Li Yucheng Shang Jinfeng Zeng Michiya Matsusaki Technology for the formation of engineered microvascular network models and their biomedical applications Nano Convergence Microvascular network Tissue engineering Biomaterials |
| title | Technology for the formation of engineered microvascular network models and their biomedical applications |
| title_full | Technology for the formation of engineered microvascular network models and their biomedical applications |
| title_fullStr | Technology for the formation of engineered microvascular network models and their biomedical applications |
| title_full_unstemmed | Technology for the formation of engineered microvascular network models and their biomedical applications |
| title_short | Technology for the formation of engineered microvascular network models and their biomedical applications |
| title_sort | technology for the formation of engineered microvascular network models and their biomedical applications |
| topic | Microvascular network Tissue engineering Biomaterials |
| url | https://doi.org/10.1186/s40580-024-00416-7 |
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