Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany
Abstract Background To assess the hysterectomy probability by calendar period and age, the overall and the age-specific prevalence of hysterectomy in women aged 30–65 years. Methods Baseline data (2005–2007) from the population-based MARZY study conducted in Mainz and Mainz-Bingen, Germany, were ana...
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BMC
2023-01-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-022-14916-w |
| _version_ | 1797952350102487040 |
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| author | Luana F. Tanaka Olaf Schoffer Jochem König Veronika Weyer-Elberich Maria Blettner Stefanie J. Klug |
| author_facet | Luana F. Tanaka Olaf Schoffer Jochem König Veronika Weyer-Elberich Maria Blettner Stefanie J. Klug |
| author_sort | Luana F. Tanaka |
| collection | DOAJ |
| description | Abstract Background To assess the hysterectomy probability by calendar period and age, the overall and the age-specific prevalence of hysterectomy in women aged 30–65 years. Methods Baseline data (2005–2007) from the population-based MARZY study conducted in Mainz and Mainz-Bingen, Germany, were analysed. 6429 women aged 30–65 years were asked whether they had undergone a hysterectomy and the date and indication of the procedure. We calculated the 5-year age-specific prevalence of hysterectomy and estimated the probability of undergoing a hysterectomy combining two approaches: 1) Kaplan–Meier and 2) Inverse probability weighting (IPW). We assessed potential changes over calendar periods by simulating survival curves, having hysterectomy as the event, employing a Cox proportional hazard model. Results Data on hysterectomy were available for 4719 women. Of these, 961 (20.4%) had undergone a hysterectomy between 1960 and 2006. The hysterectomy prevalence was highest among the 60–64 year-olds (40.7%). The IPW-corrected probability of having a hysterectomy up to the age of 65 years was 36.4%. The age-specific probability of hysterectomy increased from 0.1% (20–24 years), peaking at 45–49 years (7.8%) and declining thereafter to less than 5% among women aged 50 and older. Over time, women were hysterectomised at an increasingly older age. Most hysterectomies (86.7%) were done due to benign disease. Conclusions A shift to older age at hysterectomy with an advancing calendar period likely reflects changes in clinical practice in Germany. Trial registration Landesärztekammer Rheinland-Pfalz: 837.438.03 (4100). |
| first_indexed | 2024-04-10T22:44:56Z |
| format | Article |
| id | doaj.art-79958b815e414363929e2f2649fe0429 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-10T22:44:56Z |
| publishDate | 2023-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-79958b815e414363929e2f2649fe04292023-01-15T12:23:10ZengBMCBMC Public Health1471-24582023-01-012311910.1186/s12889-022-14916-wChanges in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, GermanyLuana F. Tanaka0Olaf Schoffer1Jochem König2Veronika Weyer-Elberich3Maria Blettner4Stefanie J. Klug5Chair of Epidemiology, TUM Department of Sport and Health Sciences, Technical University of MunichChair of Epidemiology, TUM Department of Sport and Health Sciences, Technical University of MunichInstitute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg UniversityInstitute of Biostatistics and Clinical Research, University of MünsterInstitute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center, Johannes Gutenberg UniversityChair of Epidemiology, TUM Department of Sport and Health Sciences, Technical University of MunichAbstract Background To assess the hysterectomy probability by calendar period and age, the overall and the age-specific prevalence of hysterectomy in women aged 30–65 years. Methods Baseline data (2005–2007) from the population-based MARZY study conducted in Mainz and Mainz-Bingen, Germany, were analysed. 6429 women aged 30–65 years were asked whether they had undergone a hysterectomy and the date and indication of the procedure. We calculated the 5-year age-specific prevalence of hysterectomy and estimated the probability of undergoing a hysterectomy combining two approaches: 1) Kaplan–Meier and 2) Inverse probability weighting (IPW). We assessed potential changes over calendar periods by simulating survival curves, having hysterectomy as the event, employing a Cox proportional hazard model. Results Data on hysterectomy were available for 4719 women. Of these, 961 (20.4%) had undergone a hysterectomy between 1960 and 2006. The hysterectomy prevalence was highest among the 60–64 year-olds (40.7%). The IPW-corrected probability of having a hysterectomy up to the age of 65 years was 36.4%. The age-specific probability of hysterectomy increased from 0.1% (20–24 years), peaking at 45–49 years (7.8%) and declining thereafter to less than 5% among women aged 50 and older. Over time, women were hysterectomised at an increasingly older age. Most hysterectomies (86.7%) were done due to benign disease. Conclusions A shift to older age at hysterectomy with an advancing calendar period likely reflects changes in clinical practice in Germany. Trial registration Landesärztekammer Rheinland-Pfalz: 837.438.03 (4100).https://doi.org/10.1186/s12889-022-14916-wGynaecological surgeryEpidemiologyMissing dataInverse-probability-weightingKaplan–Meier |
| spellingShingle | Luana F. Tanaka Olaf Schoffer Jochem König Veronika Weyer-Elberich Maria Blettner Stefanie J. Klug Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany BMC Public Health Gynaecological surgery Epidemiology Missing data Inverse-probability-weighting Kaplan–Meier |
| title | Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany |
| title_full | Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany |
| title_fullStr | Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany |
| title_full_unstemmed | Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany |
| title_short | Changes in the probability of hysterectomy in the city of Mainz and Mainz-Bingen region, Germany |
| title_sort | changes in the probability of hysterectomy in the city of mainz and mainz bingen region germany |
| topic | Gynaecological surgery Epidemiology Missing data Inverse-probability-weighting Kaplan–Meier |
| url | https://doi.org/10.1186/s12889-022-14916-w |
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