Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study
Irritable bowel syndrome (IBS) is a chronic disease with recurrent abdominal pain, disturbed bowel emptying, and changes in stool consistency. We compared the effectiveness of three different dietary treatment plans (G1-FM-low FODMAP diet, G2-IP IgG based elimination-rotation-diet, and as control gr...
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MDPI AG
2021-09-01
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| author | Lucyna Ostrowska Diana Wasiluk Camille F. J. Lieners Mirosława Gałęcka Anna Bartnicka Dag Tveiten |
| author_facet | Lucyna Ostrowska Diana Wasiluk Camille F. J. Lieners Mirosława Gałęcka Anna Bartnicka Dag Tveiten |
| author_sort | Lucyna Ostrowska |
| collection | DOAJ |
| description | Irritable bowel syndrome (IBS) is a chronic disease with recurrent abdominal pain, disturbed bowel emptying, and changes in stool consistency. We compared the effectiveness of three different dietary treatment plans (G1-FM-low FODMAP diet, G2-IP IgG based elimination-rotation-diet, and as control group, the G3-K control diet recommended by an attending gastroenterologist) in treating patients diagnosed with mixed irritable bowel syndrome. A total of seventy-three female patients diagnosed with a mixed form of irritable bowel syndrome (IBS-M) were enrolled in the study. The diet of each patient in Group 1 (G1-FM) and 2 (G2-IP) was determined individually during a meeting with a dietitian. Patients from Group 3 (G3-K) received nutrition advice from a gastroenterologist. Significant differences in the reduction of IBS symptoms were found between the groups. IBS symptoms as well as comorbid symptoms significantly improved or disappeared completely in the G2-IP group (idiopathic abdominal pain, <i>p</i> < 0.001; abdominal pain after a meal, <i>p</i> < 0.001; abdominal pain during defecation, <i>p</i> = 0.008), while in the G1-FM group, some of the IBS symptoms significantly improved (mucus in stool, <i>p</i> = 0.031; bloating, <i>p</i> < 0.001). In group G3-K no significant improvement was seen. Based on the results of this open-label study, it was concluded that various dietary interventions in the treatment of IBS-M patients do not uniformly affect the course and outcomes of disease management. Rotation diets based on IgG show significantly better results compared to other diets. |
| first_indexed | 2024-03-10T06:58:00Z |
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| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T06:58:00Z |
| publishDate | 2021-09-01 |
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| series | Journal of Clinical Medicine |
| spelling | doaj.art-79993b6f1a6a4c7cb73e1f80457817a42023-11-22T16:17:38ZengMDPI AGJournal of Clinical Medicine2077-03832021-09-011019431710.3390/jcm10194317Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label StudyLucyna Ostrowska0Diana Wasiluk1Camille F. J. Lieners2Mirosława Gałęcka3Anna Bartnicka4Dag Tveiten5Department of Dietetics and Clinical Nutrition, Medical University of Bialystok, ul. Mieszka I 4B, 15-054 Bialystok, PolandDepartment of Dietetics and Clinical Nutrition, Medical University of Bialystok, ul. Mieszka I 4B, 15-054 Bialystok, PolandInstitute of Microecology, ul. Sielska 10, 60-129 Poznan, PolandInstitute of Microecology, ul. Sielska 10, 60-129 Poznan, PolandInstitute of Microecology, ul. Sielska 10, 60-129 Poznan, PolandLab1 Medical Laboratory, Elias Smiths vei 10, 1337 Sandvika, NorwayIrritable bowel syndrome (IBS) is a chronic disease with recurrent abdominal pain, disturbed bowel emptying, and changes in stool consistency. We compared the effectiveness of three different dietary treatment plans (G1-FM-low FODMAP diet, G2-IP IgG based elimination-rotation-diet, and as control group, the G3-K control diet recommended by an attending gastroenterologist) in treating patients diagnosed with mixed irritable bowel syndrome. A total of seventy-three female patients diagnosed with a mixed form of irritable bowel syndrome (IBS-M) were enrolled in the study. The diet of each patient in Group 1 (G1-FM) and 2 (G2-IP) was determined individually during a meeting with a dietitian. Patients from Group 3 (G3-K) received nutrition advice from a gastroenterologist. Significant differences in the reduction of IBS symptoms were found between the groups. IBS symptoms as well as comorbid symptoms significantly improved or disappeared completely in the G2-IP group (idiopathic abdominal pain, <i>p</i> < 0.001; abdominal pain after a meal, <i>p</i> < 0.001; abdominal pain during defecation, <i>p</i> = 0.008), while in the G1-FM group, some of the IBS symptoms significantly improved (mucus in stool, <i>p</i> = 0.031; bloating, <i>p</i> < 0.001). In group G3-K no significant improvement was seen. Based on the results of this open-label study, it was concluded that various dietary interventions in the treatment of IBS-M patients do not uniformly affect the course and outcomes of disease management. Rotation diets based on IgG show significantly better results compared to other diets.https://www.mdpi.com/2077-0383/10/19/4317irritable bowel syndrome (IBS)IgG food hypersensitivityelimination-rotation dietlow-FODMAP dietclassic dietary recommendationcalprotectin |
| spellingShingle | Lucyna Ostrowska Diana Wasiluk Camille F. J. Lieners Mirosława Gałęcka Anna Bartnicka Dag Tveiten Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study Journal of Clinical Medicine irritable bowel syndrome (IBS) IgG food hypersensitivity elimination-rotation diet low-FODMAP diet classic dietary recommendation calprotectin |
| title | Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study |
| title_full | Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study |
| title_fullStr | Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study |
| title_full_unstemmed | Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study |
| title_short | Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study |
| title_sort | igg food antibody guided elimination rotation diet was more effective than fodmap diet and control diet in the treatment of women with mixed ibs results from an open label study |
| topic | irritable bowel syndrome (IBS) IgG food hypersensitivity elimination-rotation diet low-FODMAP diet classic dietary recommendation calprotectin |
| url | https://www.mdpi.com/2077-0383/10/19/4317 |
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