Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome
Posterior reversible encephalopathy syndrome (PRES) is an uncommon, subacute neurological disorder that presents radiologically with a pattern of bilateral parieto-occipital areas of vasogenic oedema. Conditions commonly associated with PRES include autoimmune disorders, cytotoxic drugs, metabolic...
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| Format: | Article |
| Language: | English |
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South African Medical Association
2022-12-01
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| Series: | South African Medical Journal |
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| Online Access: | https://samajournals.co.za/index.php/samj/article/view/634 |
| _version_ | 1797369665631027200 |
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| author | J Hiesgen T N Annor |
| author_facet | J Hiesgen T N Annor |
| author_sort | J Hiesgen |
| collection | DOAJ |
| description |
Posterior reversible encephalopathy syndrome (PRES) is an uncommon, subacute neurological disorder that presents radiologically with
a pattern of bilateral parieto-occipital areas of vasogenic oedema. Conditions commonly associated with PRES include autoimmune
disorders, cytotoxic drugs, metabolic abnormalities and, most frequently, hypertensive emergencies. Clinically, headache, visual
disturbances, seizures and an altered level of consciousness are often reported. The outcome is favourable if the underlying cause is
addressed. Posterior fossa involvement resulting in obstructive hydrocephalus is a rare presentation and may be misdiagnosed as a mass lesion or infection, leading to delayed or unnecessary treatment. We describe the clinical presentation, findings on neuroimaging and conservative management of a man with PRES resulting in severe cerebellar oedema and acute obstructive hydrocephalus. This case illustrates that awareness of atypical neuroimaging in PRES is important for the management of these patients and to avoid morbidity and mortality.
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| first_indexed | 2024-03-08T17:50:09Z |
| format | Article |
| id | doaj.art-799945a37de7458c861098a0ac484f50 |
| institution | Directory Open Access Journal |
| issn | 0256-9574 2078-5135 |
| language | English |
| last_indexed | 2024-03-08T17:50:09Z |
| publishDate | 2022-12-01 |
| publisher | South African Medical Association |
| record_format | Article |
| series | South African Medical Journal |
| spelling | doaj.art-799945a37de7458c861098a0ac484f502024-01-02T08:25:59ZengSouth African Medical AssociationSouth African Medical Journal0256-95742078-51352022-12-01113110.7196/SAMJ.2023.v113i1.16744Acute obstructive hydrocephalus in posterior reversible encephalopathy syndromeJ Hiesgen0T N Annor1Department of Neurology, School of Medicine, Faculty of Health Sciences, University of Pretoria, South AfricaDepartment of Radiology, School of Medicine, Faculty of Health Sciences, University of Pretoria, South Africa Posterior reversible encephalopathy syndrome (PRES) is an uncommon, subacute neurological disorder that presents radiologically with a pattern of bilateral parieto-occipital areas of vasogenic oedema. Conditions commonly associated with PRES include autoimmune disorders, cytotoxic drugs, metabolic abnormalities and, most frequently, hypertensive emergencies. Clinically, headache, visual disturbances, seizures and an altered level of consciousness are often reported. The outcome is favourable if the underlying cause is addressed. Posterior fossa involvement resulting in obstructive hydrocephalus is a rare presentation and may be misdiagnosed as a mass lesion or infection, leading to delayed or unnecessary treatment. We describe the clinical presentation, findings on neuroimaging and conservative management of a man with PRES resulting in severe cerebellar oedema and acute obstructive hydrocephalus. This case illustrates that awareness of atypical neuroimaging in PRES is important for the management of these patients and to avoid morbidity and mortality. https://samajournals.co.za/index.php/samj/article/view/634PRESDrugs |
| spellingShingle | J Hiesgen T N Annor Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome South African Medical Journal PRES Drugs |
| title | Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome |
| title_full | Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome |
| title_fullStr | Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome |
| title_full_unstemmed | Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome |
| title_short | Acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome |
| title_sort | acute obstructive hydrocephalus in posterior reversible encephalopathy syndrome |
| topic | PRES Drugs |
| url | https://samajournals.co.za/index.php/samj/article/view/634 |
| work_keys_str_mv | AT jhiesgen acuteobstructivehydrocephalusinposteriorreversibleencephalopathysyndrome AT tnannor acuteobstructivehydrocephalusinposteriorreversibleencephalopathysyndrome |