Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses
Oxytocin is a key hormone for parturition and maternal traits in animals. During the peripartum period, the levels of endogenous oxytocin dictate physiological events such as myometrial contractions, prostaglandin production with the subsequent increase in oxytocin receptors, and the promotion of la...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/4/768 |
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| author | Míriam Marcet-Rius Cécile Bienboire-Frosini Karina Lezama-García Adriana Domínguez-Oliva Adriana Olmos-Hernández Patricia Mora-Medina Ismael Hernández-Ávalos Alejandro Casas-Alvarado Angelo Gazzano |
| author_facet | Míriam Marcet-Rius Cécile Bienboire-Frosini Karina Lezama-García Adriana Domínguez-Oliva Adriana Olmos-Hernández Patricia Mora-Medina Ismael Hernández-Ávalos Alejandro Casas-Alvarado Angelo Gazzano |
| author_sort | Míriam Marcet-Rius |
| collection | DOAJ |
| description | Oxytocin is a key hormone for parturition and maternal traits in animals. During the peripartum period, the levels of endogenous oxytocin dictate physiological events such as myometrial contractions, prostaglandin production with the subsequent increase in oxytocin receptors, and the promotion of lactation when administered immediately after birth. While this hormone has some benefits regarding these aspects, the exogenous administration of oxytocin has been shown to have detrimental effects on the fetus, such as asphyxia, meconium staining, ruptured umbilical cords, and more dystocia cases in females. This review aims to analyze the main effects of oxytocin on myometrial activity during parturition, and its potential favorable and negative administration effects reflected in the fetus health of domestic animals. In conclusion, it is convenient to know oxytocin’s different effects as well as the adequate doses and the proper moment to administrate it, as it can reduce labor duration, but it can also increase dystocia. |
| first_indexed | 2024-03-11T09:16:05Z |
| format | Article |
| id | doaj.art-799b56a7a3054feeb8aa58ed76db8dd2 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T09:16:05Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-799b56a7a3054feeb8aa58ed76db8dd22023-11-16T18:41:20ZengMDPI AGAnimals2076-26152023-02-0113476810.3390/ani13040768Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and FetusesMíriam Marcet-Rius0Cécile Bienboire-Frosini1Karina Lezama-García2Adriana Domínguez-Oliva3Adriana Olmos-Hernández4Patricia Mora-Medina5Ismael Hernández-Ávalos6Alejandro Casas-Alvarado7Angelo Gazzano8Animal Behaviour and Welfare Department, Research Institute in Semiochemistry and Applied Ethology (IRSEA), 84400 Apt, FranceDepartment of Molecular Biology and Chemical Communication, Research Institute in Semiochemistry and Applied Ethology (IRSEA), 84400 Apt, FranceNeurophysiology, Behavior and Animal Welfare Assessment, DPAA, Universidad Autónoma Metropolitana, Xochimilco Campus, Mexico City 04960, MexicoNeurophysiology, Behavior and Animal Welfare Assessment, DPAA, Universidad Autónoma Metropolitana, Xochimilco Campus, Mexico City 04960, MexicoDivision of Biotechnology—Bioterio and Experimental Surgery, Instituto Nacional de Rehabilitación-Luis Guillermo Ibarra Ibarra (INR-LGII), Tlalpan, Mexico City 14389, MexicoFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico (UNAM), Cuautitlán 54714, MexicoFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico (UNAM), Cuautitlán 54714, MexicoNeurophysiology, Behavior and Animal Welfare Assessment, DPAA, Universidad Autónoma Metropolitana, Xochimilco Campus, Mexico City 04960, MexicoDepartment of Veterinary Sciences, University of Pisa, 56124 Pisa, ItalyOxytocin is a key hormone for parturition and maternal traits in animals. During the peripartum period, the levels of endogenous oxytocin dictate physiological events such as myometrial contractions, prostaglandin production with the subsequent increase in oxytocin receptors, and the promotion of lactation when administered immediately after birth. While this hormone has some benefits regarding these aspects, the exogenous administration of oxytocin has been shown to have detrimental effects on the fetus, such as asphyxia, meconium staining, ruptured umbilical cords, and more dystocia cases in females. This review aims to analyze the main effects of oxytocin on myometrial activity during parturition, and its potential favorable and negative administration effects reflected in the fetus health of domestic animals. In conclusion, it is convenient to know oxytocin’s different effects as well as the adequate doses and the proper moment to administrate it, as it can reduce labor duration, but it can also increase dystocia.https://www.mdpi.com/2076-2615/13/4/768oxytocindomestic animalsparturitionmeconium stainingfetal asphyxia |
| spellingShingle | Míriam Marcet-Rius Cécile Bienboire-Frosini Karina Lezama-García Adriana Domínguez-Oliva Adriana Olmos-Hernández Patricia Mora-Medina Ismael Hernández-Ávalos Alejandro Casas-Alvarado Angelo Gazzano Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses Animals oxytocin domestic animals parturition meconium staining fetal asphyxia |
| title | Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses |
| title_full | Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses |
| title_fullStr | Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses |
| title_full_unstemmed | Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses |
| title_short | Clinical Experiences and Mechanism of Action with the Use of Oxytocin Injection at Parturition in Domestic Animals: Effect on the Myometrium and Fetuses |
| title_sort | clinical experiences and mechanism of action with the use of oxytocin injection at parturition in domestic animals effect on the myometrium and fetuses |
| topic | oxytocin domestic animals parturition meconium staining fetal asphyxia |
| url | https://www.mdpi.com/2076-2615/13/4/768 |
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