Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria
Dried cyanobacteria ('Spirulina') are sold as a nutraceutical for their high content of proteins, essential fatty acids and vitamins. Beyond spirulina, other genera of cyanobacteria produce interesting small molecules that could find use in nutraceutical or pharmaceutical applicat...
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| Format: | Article |
| Language: | deu |
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Swiss Chemical Society
2011-06-01
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| Series: | CHIMIA |
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| Online Access: | https://www.chimia.ch/chimia/article/view/5038 |
| _version_ | 1819278682177404928 |
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| author | Karl Gademann |
| author_facet | Karl Gademann |
| author_sort | Karl Gademann |
| collection | DOAJ |
| description |
Dried cyanobacteria ('Spirulina') are sold as a nutraceutical for their high content of proteins, essential fatty acids and vitamins. Beyond spirulina, other genera of cyanobacteria produce interesting small molecules that could find use in nutraceutical or pharmaceutical applications.
This account presents recent research efforts on antimalarial nostocarboline and the aerucyclamides, as well as on potent toxins such as cyanopeptolin 1020 and microcystins. Combinations of spectroscopic, computational, chemical and biological studies investigated the mechanism of action of
these compounds. Their application potential with regard to nutraceuticals or pharmaceuticals is discussed.
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| first_indexed | 2024-12-24T00:15:53Z |
| format | Article |
| id | doaj.art-799d806db3c24a30b94c69c412923cd7 |
| institution | Directory Open Access Journal |
| issn | 0009-4293 2673-2424 |
| language | deu |
| last_indexed | 2024-12-24T00:15:53Z |
| publishDate | 2011-06-01 |
| publisher | Swiss Chemical Society |
| record_format | Article |
| series | CHIMIA |
| spelling | doaj.art-799d806db3c24a30b94c69c412923cd72022-12-21T17:24:44ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242011-06-0165610.2533/chimia.2011.416Out in the Green: Biologically Active Metabolites Produced by CyanobacteriaKarl Gademann0University of Basel, Department of Chemistry, St. Johanns-Ring 19, CH-4056 Basel;, Email: karl.gademann@unibas.ch Dried cyanobacteria ('Spirulina') are sold as a nutraceutical for their high content of proteins, essential fatty acids and vitamins. Beyond spirulina, other genera of cyanobacteria produce interesting small molecules that could find use in nutraceutical or pharmaceutical applications. This account presents recent research efforts on antimalarial nostocarboline and the aerucyclamides, as well as on potent toxins such as cyanopeptolin 1020 and microcystins. Combinations of spectroscopic, computational, chemical and biological studies investigated the mechanism of action of these compounds. Their application potential with regard to nutraceuticals or pharmaceuticals is discussed. https://www.chimia.ch/chimia/article/view/5038Chemical biologyMechanism of actionNatural productsOrganic synthesis |
| spellingShingle | Karl Gademann Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria CHIMIA Chemical biology Mechanism of action Natural products Organic synthesis |
| title | Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria |
| title_full | Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria |
| title_fullStr | Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria |
| title_full_unstemmed | Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria |
| title_short | Out in the Green: Biologically Active Metabolites Produced by Cyanobacteria |
| title_sort | out in the green biologically active metabolites produced by cyanobacteria |
| topic | Chemical biology Mechanism of action Natural products Organic synthesis |
| url | https://www.chimia.ch/chimia/article/view/5038 |
| work_keys_str_mv | AT karlgademann outinthegreenbiologicallyactivemetabolitesproducedbycyanobacteria |