In a novel autoimmune and high-pressure glaucoma model a complex immune response is induced

In a novel autoimmune and high-pressure glaucoma model a complex immune response is induced

BackgroundThe neurodegenerative processes leading to glaucoma are complex. In addition to elevated intraocular pressure (IOP), an involvement of immunological mechanisms is most likely. In the new multifactorial glaucoma model, a combination of high IOP and optic nerve antigen (ONA) immunization lea...

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Bibliographic Details
Main Authors: Sabrina Reinehr, Julien Wulf, Janine Theile, Kim K. Schulte, Marcus Peters, Rudolf Fuchshofer, H. Burkhard Dick, Stephanie C. Joachim
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
autoimmune glaucoma
complement system
microglia/macrophages
glaucoma animal models
immune response
intraocular pressure
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1296178/full

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